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Journal of Medicinal Chemistry|October 5, 2023
Selective and Bioavailable HDAC6 2-(Difluoromethyl)-1,3,4-oxadiazole Substrate Inhibitors and Modeling of Their Bioactivation MechanismLena Ripa, Jenny Sandmark, Glyn Hughes, et al.Bioorganic & Medicinal Chemistry Letters|February 14, 2012
Aminoimidazoles as BACE-1 inhibitors: the challenge to achieve in vivo brain efficacyBritt-Marie Swahn, Jörg Holenz, Jacob Kihlström, et al.ACS Medicinal Chemistry Letters|June 17, 2026
Discovery of a Selective Histone Deacetylase 6 Degrader (HDAC6 PROTAC) with a Short and Rigid Linker Demonstrating Sustained Knockdown of HDAC6 In VivoLena Ripa, Carlo Cassani, Glyn Hughes, et al.Mabs|December 9, 2014
Affinity maturation of a novel antagonistic human monoclonal antibody with a long VH CDR3 targeting the Class A GPCR formyl-peptide receptor 1Julie A Douthwaite, Sudharsan Sridharan, Catherine Huntington, et al.Journal of Medicinal Chemistry|January 30, 2026
Discovery of a Highly Potent and Selective Small-Molecule Inhibitor of In Vivo Anaerobic Choline Metabolism by Human Gut BacteriaMariell Pettersson, Giuseppina La Sala, Anders Gunnarsson, et al.Journal of Medicinal Chemistry|October 9, 2025
Design of Bicyclic Peptide Tandems Mimicking the Homodimeric GDF15 Protein to Inhibit GDF15-GFRaL-RET Complex Cell SignalingAnaïs F M Noisier, Jenny Sandmark, Fredrik Edfeldt, et al.Journal of Medicinal Chemistry|August 16, 2019
Discovery of the Oral Leukotriene C4 Synthase Inhibitor (1S,2S)-2-({5-[(5-Chloro-2,4-difluorophenyl)(2-fluoro-2-methylpropyl)amino]-3-methoxypyrazin-2-yl}carbonyl)cyclopropanecarboxylic Acid (AZD9898) as a New Treatment for AsthmaMagnus Munck Af Rosenschöld, Petra Johannesson, Antonios Nikitidis, et al.Pageof 2