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Methods in Molecular Biology (Clifton, N.J.)|April 3, 2024
KRAS4b:RAF-1 Homogenous Time-Resolved Fluorescence Resonance Energy Transfer Assay for Drug DiscoveryErik K Larsen, Maria Abreu-Blanco, Dana Rabara, et al.Sensors (Basel, Switzerland)|November 21, 2018
Label-Free Time-Gated Luminescent Detection Method for the Nucleotides with Varying Phosphate ContentKari Kopra, Tanja Seppälä, Dana Rabara, et al.Analytical Chemistry|February 29, 2020
Homogeneous Dual-Parametric-Coupled Assay for Simultaneous Nucleotide Exchange and KRAS/RAF-RBD Interaction MonitoringKari Kopra, Emmiliisa Vuorinen, Maria Abreu-Blanco, et al.Science Signaling|October 4, 2018
The bacterial Ras/Rap1 site-specific endopeptidase RRSP cleaves Ras through an atypical mechanism to disrupt Ras-ERK signalingMarco Biancucci, George Minasov, Avik Banerjee, et al.Methods in Molecular Biology (Clifton, N.J.)|July 25, 2024
Determining KRAS4B-Targeting Compound Specificity by Top-Down Mass SpectrometryRobert A D'Ippolito, Grace M Scheidemantle, Dana Rabara, et al.Scientific Reports|November 3, 2015
Farnesylated and methylated KRAS4b: high yield production of protein suitable for biophysical studies of prenylated protein-lipid interactionsWilliam K Gillette, Dominic Esposito, Maria Abreu Blanco, et al.Analytical Chemistry|March 18, 2024
A Top-Down Proteomic Assay to Evaluate KRAS4B-Compound EngagementRobert A D'Ippolito, Dana Rabara, Maria Abreu Blanco, et al.Cancer Discovery|December 6, 2024
Discovery of BBO-8520, a First-In-Class Direct and Covalent Dual Inhibitor of GTP-Bound (ON) and GDP-Bound (OFF) KRASG12CAnna E Maciag, James P Stice, Bin Wang, et al.Science (New York, N.Y.)|June 12, 2025
BBO-10203 inhibits tumor growth without inducing hyperglycemia by blocking RAS-PI3Kα interactionDhirendra K Simanshu, Rui Xu, James P Stice, et al.Pageof 1