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Proceedings of the National Academy of Sciences of the United States of America|November 22, 2023
The mechanism of Gα regulation of PLCβ3-catalyzed PIP2 hydrolysisMaria E Falzone, Roderick MacKinnonBiorxiv : the Preprint Server for Biology|September 11, 2023
The mechanism of Gα regulation of PLCβ3 -catalyzed PIP2 hydrolysisMaria E Falzone, Roderick MacKinnonProceedings of the National Academy of Sciences of the United States of America|May 12, 2023
Gβγ activates PIP2 hydrolysis by recruiting and orienting PLCβ on the membrane surfaceMaria E Falzone, Roderick MacKinnonMethods in Molecular Biology (Clifton, N.J.)|March 1, 2020
Reconstitution of Proteoliposomes for Phospholipid Scrambling and Nonselective Channel AssaysMaria E Falzone, Alessio AccardiBiorxiv : the Preprint Server for Biology|February 9, 2026
PLCβs are recruited to the plasma membrane in macrophages by both Gβγ and Gα qMaria E Falzone, Priyam Banerjee, Roderick MacKinnonProceedings of the National Academy of Sciences of the United States of America|July 27, 2026
PLCβs are recruited to the plasma membrane in macrophages by both Gβγ and GαqMaria E Falzone, Priyam Banerjee, Roderick MacKinnonThe Journal of General Physiology|June 20, 2018
Known structures and unknown mechanisms of TMEM16 scramblases and channelsMaria E Falzone, Mattia Malvezzi, Byoung-Cheol Lee, et al.Journal of Computational Chemistry|November 22, 2019
Membrane lipids are both the substrates and a mechanistically responsive environment of TMEM16 scramblase proteinsGeorge Khelashvili, Xiaolu Cheng, Maria E Falzone, et al.Nature Communications|November 2, 2019
Dynamic modulation of the lipid translocation groove generates a conductive ion channel in Ca2+-bound nhTMEM16George Khelashvili, Maria E Falzone, Xiaolu Cheng, et al.Biorxiv : the Preprint Server for Biology|August 1, 2026
Anionic lipids regulate PLCβ membrane recruitmentMakayla A Crawford, Marie B Bennett, Yu Qin, et al.Pageof 2