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ACS Chemical Biology|December 14, 2006
Gene silencing activity of siRNAs with a ribo-difluorotoluyl nucleotideJie Xia, Anne Noronha, Ivanka Toudjarska, et al.The Journal of Experimental Medicine|February 1, 2012
IRE1α activation protects mice against acetaminophen-induced hepatotoxicityKyu Yeon Hur, Jae-Seon So, Vera Ruda, et al.Cell Metabolism|February 14, 2012
The Scap/SREBP pathway is essential for developing diabetic fatty liver and carbohydrate-induced hypertriglyceridemia in animalsYoung-Ah Moon, Guosheng Liang, Xuefen Xie, et al.Cell Metabolism|October 9, 2012
Silencing of lipid metabolism genes through IRE1α-mediated mRNA decay lowers plasma lipids in miceJae-Seon So, Kyu Yeon Hur, Margarite Tarrio, et al.Journal of Biology|November 20, 2002
Small-molecule modulators of Hedgehog signaling: identification and characterization of Smoothened agonists and antagonistsMaria Frank-Kamenetsky, Xiaoyan M Zhang, Steve Bottega, et al.Nature Biotechnology|August 23, 2017
Control of phosphorothioate stereochemistry substantially increases the efficacy of antisense oligonucleotidesNaoki Iwamoto, David C D Butler, Nenad Svrzikapa, et al.The Journal of Clinical Investigation|April 3, 2012
Activation of ER stress and mTORC1 suppresses hepatic sortilin-1 levels in obese miceDing Ai, Juan M Baez, Hongfeng Jiang, et al.Lancet (London, England)|October 8, 2013
Effect of an RNA interference drug on the synthesis of proprotein convertase subtilisin/kexin type 9 (PCSK9) and the concentration of serum LDL cholesterol in healthy volunteers: a randomised, single-blind, placebo-controlled, phase 1 trialKevin Fitzgerald, Maria Frank-Kamenetsky, Svetlana Shulga-Morskaya, et al.Proceedings of the National Academy of Sciences of the United States of America|January 19, 2010
Lipid-like materials for low-dose, in vivo gene silencingKevin T Love, Kerry P Mahon, Christopher G Levins, et al.Molecular Therapy : the Journal of the American Society of Gene Therapy|May 13, 2010
Targeted delivery of RNAi therapeutics with endogenous and exogenous ligand-based mechanismsAkin Akinc, William Querbes, Soma De, et al.Pageof 2