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Blood|May 10, 2011
PTPN2 negatively regulates oncogenic JAK1 in T-cell acute lymphoblastic leukemiaMaria Kleppe, Jean Soulier, Vahid Asnafi, et al.Blood|January 29, 2014
Improved targeting of JAK2 leads to increased therapeutic efficacy in myeloproliferative neoplasmsNeha Bhagwat, Priya Koppikar, Matthew Keller, et al.Nature Communications|December 22, 2016
Endothelial-specific inhibition of NF-κB enhances functional haematopoiesisMichael G Poulos, Pradeep Ramalingam, Michael C Gutkin, et al.Journal of the National Cancer Institute|September 11, 2019
Evaluating Clonal Hematopoiesis in Tumor-Infiltrating Leukocytes in Breast Cancer and Secondary Hematologic MalignanciesElizabeth A Comen, Robert L Bowman, Pier Selenica, et al.Cell Reports|February 2, 2018
TRAF6 Mediates Basal Activation of NF-κB Necessary for Hematopoietic Stem Cell HomeostasisJing Fang, Tomoya Muto, Maria Kleppe, et al.Nature Genetics|May 18, 2010
Deletion of the protein tyrosine phosphatase gene PTPN2 in T-cell acute lymphoblastic leukemiaMaria Kleppe, Idoya Lahortiga, Tiama El Chaar, et al.Cell Stem Cell|October 3, 2017
Jak1 Integrates Cytokine Sensing to Regulate Hematopoietic Stem Cell Function and Stress HematopoiesisMaria Kleppe, Matthew H Spitzer, Sheng Li, et al.NPJ Breast Cancer|July 20, 2017
Somatic mutations in leukocytes infiltrating primary breast cancersMaria Kleppe, Elizabeth Comen, Hannah Y Wen, et al.The Journal of Clinical Investigation|February 8, 2019
Targeting compensatory MEK/ERK activation increases JAK inhibitor efficacy in myeloproliferative neoplasmsSimona Stivala, Tamara Codilupi, Sime Brkic, et al.Blood|March 10, 2021
A JAK/STAT-mediated inflammatory signaling cascade drives oncogenesis in AF10-rearranged AMLBo-Rui Chen, Anagha Deshpande, Karina Barbosa, et al.Pageof 4