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Journal of Medicinal Chemistry|June 30, 2022
Innovative Non-PrP-Targeted Drug Strategy Designed to Enhance Prion ClearanceArianna Colini Baldeschi, Marco Zattoni, Silvia Vanni, et al.
ACS Chemical Neuroscience|November 29, 2022
Discovery of Dual Aβ/Tau Inhibitors and Evaluation of Their Therapeutic Effect on a <i>Drosophila</i> Model of Alzheimer's DiseaseAnnachiara Gandini, Ana Elisa Gonçalves, Silvia Strocchi, et al.
European Journal of Medicinal Chemistry|June 20, 2025
Design, synthesis and pharmacological evaluation of multitarget GPR40 agonists/HDAC6 inhibitors for Alzheimer's diseasePedro de Sena M Pinheiro, Francesca de Chirico, Manuela Loi, et al.
Plos Neglected Tropical Diseases|January 26, 2013
Naphthoquinone derivatives exert their antitrypanosomal activity via a multi-target mechanismSimone Pieretti, Jurgen R Haanstra, Muriel Mazet, et al.
Journal of Medicinal Chemistry|September 27, 2014
Multitarget drug design strategy: quinone-tacrine hybrids designed to block amyloid-β aggregation and to exert anticholinesterase and antioxidant effectsEugenie Nepovimova, Elisa Uliassi, Jan Korabecny, et al.
European Journal of Medicinal Chemistry|June 30, 2018
Tacripyrimidines, the first tacrine-dihydropyrimidine hybrids, as multi-target-directed ligands for Alzheimer's diseaseMourad Chioua, Eleonora Buzzi, Ignacio Moraleda, et al.
Chemmedchem|January 22, 2019
Discovery of Sustainable Drugs for Neglected Tropical Diseases: Cashew Nut Shell Liquid (CNSL)-Based Hybrids Target Mitochondrial Function and ATP Production in Trypanosoma bruceiMichela Cerone, Elisa Uliassi, Federica Prati, et al.
International Journal of Molecular Sciences|November 11, 2022
In Vitro and In Silico Analysis of New n-Butyl and Isobutyl Quinoxaline-7-carboxylate 1,4-di-<i>N</i>-oxide Derivatives against <i>Trypanosoma cruzi</i> as Trypanothione Reductase InhibitorsAlonzo González-González, Oscar Sánchez-Sánchez, R Luise Krauth-Siegel, et al.
ACS Infectious Diseases|June 12, 2023
Valorizing Constituents of Cashew Nut Shell Liquid toward the Sustainable Development of New Drugs against Chagas DiseaseLaís Flávia Nunes Lemes, George E Magoulas, Andressa Souza de Oliveira, et al.
Molecules (Basel, Switzerland)|February 4, 2017
Trypanocidal Activity of Quinoxaline 1,4 Di-N-oxide Derivatives as Trypanothione Reductase InhibitorsKarla Fabiola Chacón-Vargas, Benjamin Nogueda-Torres, Luvia E Sánchez-Torres, et al.
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