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Molecules (Basel, Switzerland)|January 8, 2025
Targeting EZH2 in Cancer: Mechanisms, Pathways, and Therapeutic PotentialMaria Saveria Gilardini Montani, Rossella Benedetti, Mara CironeBiochimica Et Biophysica Acta|August 20, 2005
Sodium butyrate sensitises human pancreatic cancer cells to both the intrinsic and the extrinsic apoptotic pathwaysFederica Natoni, Laura Diolordi, Claudio Santoni, et al.Oncotarget|September 5, 2015
Capsaicin triggers immunogenic PEL cell death, stimulates DCs and reverts PEL-induced immune suppressionMarisa Granato, Maria Saveria Gilardini Montani, Mariarosari Filardi, et al.Journal of Medicinal Chemistry|July 31, 2015
Hydroxytyrosol-Derived Compounds: A Basis for the Creation of New Pharmacological Agents for Cancer Prevention and TherapyRoberta Bernini, Maria Saveria Gilardini Montani, Nicolò Merendino, et al.Experimental Hematology|January 9, 2023
JQ-1/bortezomib combination strongly impairs MM and PEL survival by inhibiting c-Myc and mTOR despite the activation of prosurvival mechanismsAndrea Arena, Maria Anele Romeo, Rossella Benedetti, et al.Biomedicines|April 23, 2022
Targeting c-Myc Unbalances UPR towards Cell Death and Impairs DDR in Lymphoma and Multiple Myeloma CellsAndrea Arena, Maria Anele Romeo, Rossella Benedetti, et al.Biochemical and Biophysical Research Communications|May 8, 2022
The impairment of DDR reduces XBP1s, further increasing DNA damage, and triggers autophagy via PERK/eIF2alpha in MM and IRE1alpha/JNK1/2 in PEL cellsAndrea Arena, Maria Anele Romeo, Rossella Benedetti, et al.Cell Death Discovery|April 10, 2025
Mutant p53 upregulates HDAC6 to resist ER stress and facilitates Ku70 deacetylation, which prevents its degradation and mitigates DNA damage in colon cancer cellsRossella Benedetti, Michele Di Crosta, Maria Saveria Gilardini Montani, et al.Current Issues in Molecular Biology|March 27, 2024
5-AZA Upregulates SOCS3 and PTPN6/SHP1, Inhibiting STAT3 and Potentiating the Effects of AG490 against Primary Effusion Lymphoma CellsMichele Di Crosta, Andrea Arena, Rossella Benedetti, et al.Journal of Experimental & Clinical Cancer Research : CR|November 29, 2017
Apigenin, by activating p53 and inhibiting STAT3, modulates the balance between pro-apoptotic and pro-survival pathways to induce PEL cell deathMarisa Granato, Maria Saveria Gilardini Montani, Roberta Santarelli, et al.Pageof 8