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The EMBO Journal|February 2, 2012
DNA methylation profiling identifies epigenetic dysregulation in pancreatic islets from type 2 diabetic patientsMichael Volkmar, Sarah Dedeurwaerder, Daniel A Cunha, et al.
Diabetes|July 10, 2012
Death protein 5 and p53-upregulated modulator of apoptosis mediate the endoplasmic reticulum stress-mitochondrial dialog triggering lipotoxic rodent and human β-cell apoptosisDaniel A Cunha, Mariana Igoillo-Esteve, Esteban N Gurzov, et al.
Plos Genetics|March 14, 2012
The human pancreatic islet transcriptome: expression of candidate genes for type 1 diabetes and the impact of pro-inflammatory cytokinesDécio L Eizirik, Michael Sammeth, Thomas Bouckenooghe, et al.
Frontiers in Cell and Developmental Biology|September 5, 2022
In depth functional characterization of human induced pluripotent stem cell-derived beta cells in vitro and in vivoFederica Fantuzzi, Sanna Toivonen, Andrea Alex Schiavo, et al.
Diabetes|September 21, 2017
JNK Activation of BIM Promotes Hepatic Oxidative Stress, Steatosis, and Insulin Resistance in ObesitySara A Litwak, Lokman Pang, Sandra Galic, et al.
Nucleic Acids Research|September 25, 2018
Pancreatic β-cell tRNA hypomethylation and fragmentation link TRMT10A deficiency with diabetesCristina Cosentino, Sanna Toivonen, Esteban Diaz Villamil, et al.
Plos Genetics|November 9, 2013
tRNA methyltransferase homolog gene TRMT10A mutation in young onset diabetes and primary microcephaly in humansMariana Igoillo-Esteve, Anne Genin, Nelle Lambert, et al.
Molecular Therapy. Nucleic Acids|April 28, 2025
An inflammation-associated lncRNA induces neuronal damage via mitochondrial dysfunctionAne Olazagoitia-Garmendia, Henar Rojas-Márquez, Tim Trobisch, et al.
JCI Insight|December 27, 2019
Exenatide induces frataxin expression and improves mitochondrial function in Friedreich ataxiaMariana Igoillo-Esteve, Ana F Oliveira, Cristina Cosentino, et al.
Annals of Neurology|January 3, 2013
Central role and mechanisms of β-cell dysfunction and death in friedreich ataxia-associated diabetesMiriam Cnop, Mariana Igoillo-Esteve, Myriam Rai, et al.
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