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The Journal of Biological Chemistry|July 13, 2026
A covalent inhibitor targeting Cys-349 of LIMK1 confers selectivity over LIMK2Jon B Patteson, Ioannis Manolaridis, Mee Ra Hong, et al.Journal of Medicinal Chemistry|December 4, 2010
Synthesis and pharmacological evaluation of N-(3-(1H-indol-4-yl)-5-(2-methoxyisonicotinoyl)phenyl)methanesulfonamide (LP-261), a potent antimitotic agentRupa S Shetty, Younghee Lee, Bin Liu, et al.ACS Medicinal Chemistry Letters|January 25, 2021
Discovery of an Anion-Dependent Farnesyltransferase Inhibitor from a Phenotypic ScreenMarina Bukhtiyarova, Erica M Cook, Paula J Hancock, et al.Bioorganic & Medicinal Chemistry Letters|August 3, 2020
Identification of potent inhibitors of the sortilin-progranulin interactionShawn J Stachel, Anthony T Ginnetti, Scott A Johnson, et al.Proceedings of the National Academy of Sciences of the United States of America|January 1, 2017
Structural characterization of nonactive site, TrkA-selective kinase inhibitorsHua-Poo Su, Keith Rickert, Christine Burlein, et al.Science Translational Medicine|February 22, 2023
Potent targeted activator of cell kill molecules eliminate cells expressing HIV-1Carl J Balibar, Daniel J Klein, Beata Zamlynny, et al.Nature Microbiology|April 22, 2024
Cerastecins inhibit membrane lipooligosaccharide transport in drug-resistant Acinetobacter baumanniiHao Wang, Andrii Ishchenko, Jason Skudlarek, et al.Journal of Medicinal Chemistry|August 22, 2024
Cerastecin Inhibition of the Lipooligosaccharide Transporter MsbA to Combat Acinetobacter baumannii: From Screening Impurity to In Vivo EfficacyJason W Skudlarek, Andrew J Cooke, Helen J Mitchell, et al.Pageof 2