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CPT: Pharmacometrics & Systems Pharmacology|July 17, 2021
Prediction of the drug-drug interaction potential of the α1-acid glycoprotein bound, CYP3A4/CYP2C9 metabolized oncology drug, erdafitinibLoeckie De Zwart, Jan Snoeys, Frank Jacobs, et al.International Journal of Molecular Sciences|April 20, 2016
In Vitro Model for Hepatotoxicity Studies Based on Primary Human Hepatocyte Cultivation in a Perfused 3D Bioreactor SystemFanny Knöspel, Frank Jacobs, Nora Freyer, et al.Proceedings of the National Academy of Sciences of the United States of America|November 6, 2007
In silico and in vitro pharmacogenetic analysis in miceYingying Guo, Peng Lu, Erin Farrell, et al.European Journal of Pharmaceutical Sciences : Official Journal of the European Federation for Pharmaceutical Sciences|January 26, 2025
Human organotypic colon in vitro microtissue: unveiling a new window into colonic drug dispositionPedro G M Canhão, Jan Snoeys, Suzy Geerinckx, et al.Antiviral Research|February 11, 2026
Optimal preclinical models for human dose projection of SARS-CoV-2 small molecule direct-acting antiviralsFrancesca Toselli, Sofie Jacobs, Els Scheers, et al.Toxicology and Applied Pharmacology|July 31, 2020
The utility of a differentiated preclinical liver model, HepaRG cells, in investigating delayed toxicity via inhibition of mitochondrial-replication induced by fialuridineCarol E Jolly, Oisin Douglas, Laleh Kamalian, et al.Clinical Pharmacokinetics|April 11, 2021
Clinical Investigation on Endogenous Biomarkers to Predict Strong OAT-Mediated Drug-Drug InteractionsMarie-Emilie Willemin, Thomas K Van Der Made, Ils Pijpers, et al.Toxicology in Vitro : an International Journal Published in Association with BIBRA|August 13, 2018
Establishing a systematic framework to characterise in vitro methods for human hepatic metabolic clearanceVarvara Gouliarmou, Alfonso Maria Lostia, Sandra Coecke, et al.European Journal of Pharmaceutical Sciences : Official Journal of the European Federation for Pharmaceutical Sciences|May 27, 2023
Intestinal organoids as an in vitro platform to characterize disposition, metabolism, and safety profile of small moleculesStephanie Kourula, Merel Derksen, Ferran Jardi, et al.Journal of Medicinal Chemistry|June 17, 2008
Discovery of novel, potent benzamide inhibitors of 11beta-hydroxysteroid dehydrogenase type 1 (11beta-HSD1) exhibiting oral activity in an enzyme inhibition ex vivo modelLisa D Julian, Zhulun Wang, Tracy Bostick, et al.Pageof 5