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Chemical Biology & Drug Design|September 28, 2023
A phenotypic screen with Trypanosoma brucei for discovering small molecules that target the SLiM-binding pocket of proliferating cell nuclear antigen orthologsMarisa Actis, Naoaki Fujii, Zachary B MackeyACS Chemical Biology|June 1, 2023
Design of Class I/IV Bromodomain-Targeting Degraders for Chromatin Remodeling ComplexesHuda Zahid, Jeff P Costello, Yao Li, et al.Cell Death and Differentiation|June 21, 2022
Ca<sup>2+</sup>-mediated mitochondrial inner membrane permeabilization induces cell death independently of Bax and BakGiovanni Quarato, Fabien Llambi, Cliff S Guy, et al.Biorxiv : the Preprint Server for Biology|July 17, 2025
LCK-targeting molecular glues overcome resistance to inhibitor-based therapy in T-cell acute lymphoblastic leukemiaJun J Yang, Gisele Nishiguchi, Satoshi Yoshimura, et al.Blood|June 5, 2026
LCK-targeting molecular glues overcome resistance to inhibitor-based therapy in T-cell acute lymphoblastic leukemiaJun J Yang, Satoshi Yoshimura, Marisa Actis, et al.Journal of Medicinal Chemistry|July 8, 2024
Development of an Orally Bioavailable LCK PROTAC Degrader as a Potential Therapeutic Approach to T-Cell Acute Lymphoblastic LeukemiaJamie A Jarusiewicz, Satoshi Yoshimura, Marisa Actis, et al.ACS Medicinal Chemistry Letters|March 18, 2022
Development of Potent and Selective Janus Kinase 2/3 Directing PG-PROTACsLisa J Alcock, Yunchao Chang, Jamie A Jarusiewicz, et al.ACS Medicinal Chemistry Letters|February 16, 2023
Phenyl Dihydrouracil: An Alternative Cereblon Binder for PROTAC DesignJamie A Jarusiewicz, Satoshi Yoshimura, Anand Mayasundari, et al.Science Translational Medicine|August 24, 2022
Preclinical evaluation of proteolytic targeting of LCK as a therapeutic approach in T cell acute lymphoblastic leukemiaJianzhong Hu, Jamie Jarusiewicz, Guoqing Du, et al.Nature Communications|August 20, 2025
Unbiased mapping of cereblon neosubstrate landscape by high-throughput proteomicsMartin Steger, Gisele Nishiguchi, Qiong Wu, et al.Pageof 2