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Investigational New Drugs|July 1, 2015
P-glycoprotein and breast cancer resistance protein restrict the brain penetration of the CDK4/6 inhibitor palbociclibMark C de Gooijer, Ping Zhang, Nishita Thota, et al.Scientific Reports|July 19, 2018
Buparlisib is a brain penetrable pan-PI3K inhibitorMark C de Gooijer, Ping Zhang, Levi C M Buil, et al.Fluids and Barriers of the CNS|August 5, 2024
ATP-binding cassette transporter inhibitor potency and substrate drug affinity are critical determinants of successful drug delivery enhancement to the brainAristeidis Lentzas, Mark C de Gooijer, Stefanie Zuidema, et al.Cell Death and Differentiation|December 20, 2024
Senolysis by ABT-263 is associated with inherent apoptotic dependence of cancer cells derived from the non-senescent stateFleur Jochems, Chrysiida Baltira, Julie A MacDonald, et al.Neoplasia (New York, N.Y.)|June 1, 2018
Improved Brain Penetration and Antitumor Efficacy of Temozolomide by Inhibition of ABCB1 and ABCG2Mark C de Gooijer, Nienke A de Vries, Tessa Buckle, et al.Cell Reports. Medicine|February 1, 2021
ATP-binding cassette transporters restrict drug delivery and efficacy against brain tumors even when blood-brain barrier integrity is lostMark C de Gooijer, E Marleen Kemper, Levi C M Buil, et al.Cell Reports. Medicine|June 19, 2024
The impact of ATP-binding cassette transporters in the diseased brain: Context mattersChrysiida Baltira, Eleonora Aronica, William F Elmquist, et al.STAR Protocols|April 4, 2022
Protocol for live-cell imaging during Tumor Treating Fields treatment with Inovitro LivePaul L G Slangen, Yaara Porat, Marjolijn Mertz, et al.Clinical Cancer Research : an Official Journal of the American Association for Cancer Research|August 25, 2016
PI3K-mTOR Pathway Inhibition Exhibits Efficacy Against High-grade Glioma in Clinically Relevant Mouse ModelsFan Lin, Mark C de Gooijer, Diana Hanekamp, et al.Clinical Cancer Research : an Official Journal of the American Association for Cancer Research|March 21, 2014
ABCB1, ABCG2, and PTEN determine the response of glioblastoma to temozolomide and ABT-888 therapyFan Lin, Mark C de Gooijer, Eloy Moreno Roig, et al.Pageof 3