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Bioorganic & Medicinal Chemistry|July 16, 2010
The structure-activity relationships of A-ring-substituted aromathecin topoisomerase I inhibitors strongly support a camptothecin-like binding modeMaris A Cinelli, Andrew E Morrell, Thomas S Dexheimer, et al.Journal of Medicinal Chemistry|July 11, 2003
Design, synthesis, and biological evaluation of cytotoxic 11-alkenylindenoisoquinoline topoisomerase I inhibitors and indenoisoquinoline-camptothecin hybridsBrian M Fox, Xiangshu Xiao, Smitha Antony, et al.Acta Crystallographica. Section D, Biological Crystallography|September 9, 2010
Structural study and thermodynamic characterization of inhibitor binding to lumazine synthase from Bacillus anthracisEkaterina Morgunova, Boris Illarionov, Sabine Saller, et al.Biochemistry|February 23, 2005
Crystal structure of lumazine synthase from Mycobacterium tuberculosis as a target for rational drug design: binding mode of a new class of purinetrione inhibitorsEkaterina Morgunova, Winfried Meining, Boris Illarionov, et al.Journal of the American Chemical Society|February 11, 2010
Mechanistic insights on riboflavin synthase inspired by selective binding of the 6,7-dimethyl-8-ribityllumazine exomethylene anionRyu-Ryun Kim, Boris Illarionov, Monika Joshi, et al.Bioorganic & Medicinal Chemistry|February 25, 2016
Synthesis and biological evaluation of new fluorinated and chlorinated indenoisoquinoline topoisomerase I poisonsDaniel E Beck, Wei Lv, Monica Abdelmalak, et al.Journal of Medicinal Chemistry|October 29, 2004
Synthesis and anticancer activity of simplified indenoisoquinoline topoisomerase I inhibitors lacking substituents on the aromatic ringsMuthukaman Nagarajan, Andrew Morrell, Brian C Fort, et al.The Journal of Organic Chemistry|April 2, 2002
Investigation of the binding of epimer A of the covalent hydrate of 6,7-bis(trifluoromethyl)-8-D-ribityllumazine to a recombinant F22W Bacillus subtilis lumazine synthase mutant by (15)N[(19)F] REDOR NMRAnil K Mehta, Daniel R Studelska, Markus Fischer, et al.Journal of Molecular Biology|February 13, 2003
Enzyme catalysis via control of activation entropy: site-directed mutagenesis of 6,7-dimethyl-8-ribityllumazine synthaseMarkus Fischer, Ilka Haase, Klaus Kis, et al.Journal of Medicinal Chemistry|October 13, 2006
Synthesis and evaluation of indenoisoquinoline topoisomerase I inhibitors substituted with nitrogen heterocyclesMuthukaman Nagarajan, Andrew Morrell, Alexandra Ioanoviciu, et al.Pageof 18