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Journal of Medicinal Chemistry
|
April 22, 2015
Discovery of a β-Hairpin Octapeptide, c[Pro-Arg-Phe-Phe-Dap-Ala-Phe-DPro], Mimetic of Agouti-Related Protein(87-132) [AGRP(87-132)] with Equipotent Mouse Melanocortin-4 Receptor (mMC4R) Antagonist Pharmacology
Mark D Ericson, Andrzej Wilczynski, Nicholas B Sorensen, et al.
ACS Medicinal Chemistry Letters
|
January 25, 2021
Multiresidue Tetrapeptide Substitutions Yield a 140-fold Selective Melanocortin-3 over Melanocortin-4 Receptor Agonist
Mark D Ericson, Romessa Shaikh, Courtney M Larson, et al.
Journal of Medicinal Chemistry
|
August 17, 2017
Structure-Activity Relationship Studies on a Macrocyclic Agouti-Related Protein (AGRP) Scaffold Reveal Agouti Signaling Protein (ASP) Residue Substitutions Maintain Melanocortin-4 Receptor Antagonist Potency and Result in Inverse Agonist Pharmacology at the Melanocortin-5 Receptor
Mark D Ericson, Katie T Freeman, Sathya M Schnell, et al.
ACS Chemical Neuroscience
|
June 21, 2018
Arg-Phe-Phe d-Amino Acid Stereochemistry Scan in the Macrocyclic Agouti-Related Protein Antagonist Scaffold c[Pro-Arg-Phe-Phe-Xxx-Ala-Phe-DPro] Results in Unanticipated Melanocortin-1 Receptor Agonist Profiles
Mark D Ericson, Zoe M Koerperich, Katie T Freeman, et al.
ACS Omega
|
August 15, 2022
Incorporation of Indoylated Phenylalanine Yields a Sub-Micromolar Selective Melanocortin-4 Receptor Antagonist Tetrapeptide
Mark D Ericson, Courtney M Larson, Katie T Freeman, et al.
Molecules (Basel, Switzerland)
|
April 25, 2019
Structure⁻Activity Relationships of the Tetrapeptide Ac-His-Arg-(<i>p</i>I)DPhe-Tic-NH<sub>2</sub> at the Mouse Melanocortin Receptors: Modification at the (<i>p</i>I)DPhe Position Leads to mMC3R Versus mMC4R Selective Ligands
Katherine N Schlasner, Mark D Ericson, Skye R Doering, et al.
Biochimica Et Biophysica Acta. Molecular Basis of Disease
|
April 2, 2017
Bench-top to clinical therapies: A review of melanocortin ligands from 1954 to 2016
Mark D Ericson, Cody J Lensing, Katlyn A Fleming, et al.
ACS Chemical Neuroscience
|
May 3, 2016
Comparative Functional Alanine Positional Scanning of the α-Melanocyte Stimulating Hormone and NDP-Melanocyte Stimulating Hormone Demonstrates Differential Structure-Activity Relationships at the Mouse Melanocortin Receptors
Aleksandar Todorovic, Mark D Ericson, Ryan D Palusak, et al.
ACS Chemical Neuroscience
|
January 25, 2018
Structure-Activity Relationship Studies of a Macrocyclic AGRP-Mimetic Scaffold c[Pro-Arg-Phe-Phe-Asn-Ala-Phe-DPro] Yield Potent and Selective Melanocortin-4 Receptor Antagonists and Melanocortin-5 Receptor Inverse Agonists That Increase Food Intake in Mice
Katlyn A Fleming, Mark D Ericson, Katie T Freeman, et al.
Journal of Medicinal Chemistry
|
December 18, 2019
Incorporation of Agouti-Related Protein (AgRP) Human Single Nucleotide Polymorphisms (SNPs) in the AgRP-Derived Macrocyclic Scaffold c[Pro-Arg-Phe-Phe-Asn-Ala-Phe-dPro] Decreases Melanocortin-4 Receptor Antagonist Potency and Results in the Discovery of Melanocortin-5 Receptor Antagonists
Zoe M Koerperich, Mark D Ericson, Katie T Freeman, et al.
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Search research articles
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Showing results (11-20 of 32) with videos related to
Sort By:
Page
of 4
Journal of Medicinal Chemistry
|
April 22, 2015
Discovery of a β-Hairpin Octapeptide, c[Pro-Arg-Phe-Phe-Dap-Ala-Phe-DPro], Mimetic of Agouti-Related Protein(87-132) [AGRP(87-132)] with Equipotent Mouse Melanocortin-4 Receptor (mMC4R) Antagonist Pharmacology
Mark D Ericson, Andrzej Wilczynski, Nicholas B Sorensen, et al.
ACS Medicinal Chemistry Letters
|
January 25, 2021
Multiresidue Tetrapeptide Substitutions Yield a 140-fold Selective Melanocortin-3 over Melanocortin-4 Receptor Agonist
Mark D Ericson, Romessa Shaikh, Courtney M Larson, et al.
Journal of Medicinal Chemistry
|
August 17, 2017
Structure-Activity Relationship Studies on a Macrocyclic Agouti-Related Protein (AGRP) Scaffold Reveal Agouti Signaling Protein (ASP) Residue Substitutions Maintain Melanocortin-4 Receptor Antagonist Potency and Result in Inverse Agonist Pharmacology at the Melanocortin-5 Receptor
Mark D Ericson, Katie T Freeman, Sathya M Schnell, et al.
ACS Chemical Neuroscience
|
June 21, 2018
Arg-Phe-Phe d-Amino Acid Stereochemistry Scan in the Macrocyclic Agouti-Related Protein Antagonist Scaffold c[Pro-Arg-Phe-Phe-Xxx-Ala-Phe-DPro] Results in Unanticipated Melanocortin-1 Receptor Agonist Profiles
Mark D Ericson, Zoe M Koerperich, Katie T Freeman, et al.
ACS Omega
|
August 15, 2022
Incorporation of Indoylated Phenylalanine Yields a Sub-Micromolar Selective Melanocortin-4 Receptor Antagonist Tetrapeptide
Mark D Ericson, Courtney M Larson, Katie T Freeman, et al.
Molecules (Basel, Switzerland)
|
April 25, 2019
Structure⁻Activity Relationships of the Tetrapeptide Ac-His-Arg-(<i>p</i>I)DPhe-Tic-NH<sub>2</sub> at the Mouse Melanocortin Receptors: Modification at the (<i>p</i>I)DPhe Position Leads to mMC3R Versus mMC4R Selective Ligands
Katherine N Schlasner, Mark D Ericson, Skye R Doering, et al.
Biochimica Et Biophysica Acta. Molecular Basis of Disease
|
April 2, 2017
Bench-top to clinical therapies: A review of melanocortin ligands from 1954 to 2016
Mark D Ericson, Cody J Lensing, Katlyn A Fleming, et al.
ACS Chemical Neuroscience
|
May 3, 2016
Comparative Functional Alanine Positional Scanning of the α-Melanocyte Stimulating Hormone and NDP-Melanocyte Stimulating Hormone Demonstrates Differential Structure-Activity Relationships at the Mouse Melanocortin Receptors
Aleksandar Todorovic, Mark D Ericson, Ryan D Palusak, et al.
ACS Chemical Neuroscience
|
January 25, 2018
Structure-Activity Relationship Studies of a Macrocyclic AGRP-Mimetic Scaffold c[Pro-Arg-Phe-Phe-Asn-Ala-Phe-DPro] Yield Potent and Selective Melanocortin-4 Receptor Antagonists and Melanocortin-5 Receptor Inverse Agonists That Increase Food Intake in Mice
Katlyn A Fleming, Mark D Ericson, Katie T Freeman, et al.
Journal of Medicinal Chemistry
|
December 18, 2019
Incorporation of Agouti-Related Protein (AgRP) Human Single Nucleotide Polymorphisms (SNPs) in the AgRP-Derived Macrocyclic Scaffold c[Pro-Arg-Phe-Phe-Asn-Ala-Phe-dPro] Decreases Melanocortin-4 Receptor Antagonist Potency and Results in the Discovery of Melanocortin-5 Receptor Antagonists
Zoe M Koerperich, Mark D Ericson, Katie T Freeman, et al.
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of 4