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Cell|December 20, 2014
Apoptotic caspases suppress mtDNA-induced STING-mediated type I IFN productionMichael J White, Kate McArthur, Donald Metcalf, et al.Plos Biology|May 2, 2024
Key residues in the VDAC2-BAK complex can be targeted to modulate apoptosisZheng Yuan, Mark F van Delft, Mark Xiang Li, et al.Cancer Cell|November 14, 2006
The BH3 mimetic ABT-737 targets selective Bcl-2 proteins and efficiently induces apoptosis via Bak/Bax if Mcl-1 is neutralizedMark F van Delft, Andrew H Wei, Kylie D Mason, et al.Science (New York, N.Y.)|February 10, 2007
Apoptosis initiated when BH3 ligands engage multiple Bcl-2 homologs, not Bax or BakSimon N Willis, Jamie I Fletcher, Thomas Kaufmann, et al.Oncotarget|February 11, 2017
SMYD2 lysine methyltransferase regulates leukemia cell growth and regeneration after genotoxic stressAdi Zipin-Roitman, Nasma Aqaqe, Muhammad Yassin, et al.Cell Death & Disease|April 2, 2022
The Lck inhibitor, AMG-47a, blocks necroptosis and implicates RIPK1 in signalling downstream of MLKLAnnette V Jacobsen, Catia L Pierotti, Kym N Lowes, et al.The Biochemical Journal|April 28, 2023
The VEGFR/PDGFR tyrosine kinase inhibitor, ABT-869, blocks necroptosis by targeting RIPK1 kinaseCatia L Pierotti, Annette V Jacobsen, Christoph Grohmann, et al.Molecular Cell|November 18, 2017
Conversion of Bim-BH3 from Activator to Inhibitor of Bak through Structure-Based DesignJason M Brouwer, Ping Lan, Angus D Cowan, et al.Science Advances|March 5, 2025
Differential regulation of BAX and BAK apoptotic activity revealed by small moleculesKaiming Li, Yu Q Yap, Donia M Moujalled, et al.Cell Death and Differentiation|April 9, 2025
Re-appraising assays on permeabilized blood cancer cells testing venetoclax or other BH3 mimetic agents selectively targeting pro-survival BCL2 proteinsJia-Nan Gong, Tirta M Djajawi, Donia M Moujalled, et al.Pageof 3