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Pharmacology Research & Perspectives
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April 22, 2020
Pharmacokinetics, mass balance, tissue distribution, metabolism, and excretion of praliciguat, a clinical-stage soluble guanylate cyclase stimulator in rats
Ali R Banijamali, Andrew E Carvalho, James D Wakefield, et al.
United European Gastroenterology Journal
|
February 6, 2015
Comparison of adequate relief with symptom, global, and responder endpoints in linaclotide phase 3 trials in IBS-C
Michael Camilleri, Anthony J Lembo, Bernard J Lavins, et al.
The Journal of Pharmacology and Experimental Therapeutics
|
October 24, 2012
Pharmacologic properties, metabolism, and disposition of linaclotide, a novel therapeutic peptide approved for the treatment of irritable bowel syndrome with constipation and chronic idiopathic constipation
Robert W Busby, Marco M Kessler, Wilmin P Bartolini, et al.
The Journal of Pharmacology and Experimental Therapeutics
|
July 29, 2015
MRP4 Modulation of the Guanylate Cyclase-C/cGMP Pathway: Effects on Linaclotide-Induced Electrolyte Secretion and cGMP Efflux
Boris Tchernychev, Pei Ge, Marco M Kessler, et al.
Plos One
|
July 30, 2015
Linaclotide in Chronic Idiopathic Constipation Patients with Moderate to Severe Abdominal Bloating: A Randomized, Controlled Trial
Brian E Lacy, Ron Schey, Steven J Shiff, et al.
Journal of Medicinal Chemistry
|
April 5, 2002
Synthesis and biological characterization of L-N(6)-(1-iminoethyl)lysine 5-tetrazole-amide, a prodrug of a selective iNOS inhibitor
E Ann Hallinan, Sofya Tsymbalov, Clifford R Dorn, et al.
European Journal of Pharmacology
|
September 25, 2010
Linaclotide, through activation of guanylate cyclase C, acts locally in the gastrointestinal tract to elicit enhanced intestinal secretion and transit
Robert W Busby, Alexander P Bryant, Wilmin P Bartolini, et al.
Life Sciences
|
March 24, 2010
Linaclotide is a potent and selective guanylate cyclase C agonist that elicits pharmacological effects locally in the gastrointestinal tract
Alexander P Bryant, Robert W Busby, Wilmin P Bartolini, et al.
Journal of Gastroenterology and Hepatology
|
January 11, 2018
Linaclotide in irritable bowel syndrome with constipation: A Phase 3 randomized trial in China and other regions
Yunsheng Yang, Jingyuan Fang, Xiaozhong Guo, et al.
The American Journal of Gastroenterology
|
September 19, 2012
Linaclotide for irritable bowel syndrome with constipation: a 26-week, randomized, double-blind, placebo-controlled trial to evaluate efficacy and safety
William D Chey, Anthony J Lembo, Bernard J Lavins, et al.
Page
of 5
Search research articles
Search
Showing results (21-30 of 43) with videos related to
Sort By:
Page
of 5
Pharmacology Research & Perspectives
|
April 22, 2020
Pharmacokinetics, mass balance, tissue distribution, metabolism, and excretion of praliciguat, a clinical-stage soluble guanylate cyclase stimulator in rats
Ali R Banijamali, Andrew E Carvalho, James D Wakefield, et al.
United European Gastroenterology Journal
|
February 6, 2015
Comparison of adequate relief with symptom, global, and responder endpoints in linaclotide phase 3 trials in IBS-C
Michael Camilleri, Anthony J Lembo, Bernard J Lavins, et al.
The Journal of Pharmacology and Experimental Therapeutics
|
October 24, 2012
Pharmacologic properties, metabolism, and disposition of linaclotide, a novel therapeutic peptide approved for the treatment of irritable bowel syndrome with constipation and chronic idiopathic constipation
Robert W Busby, Marco M Kessler, Wilmin P Bartolini, et al.
The Journal of Pharmacology and Experimental Therapeutics
|
July 29, 2015
MRP4 Modulation of the Guanylate Cyclase-C/cGMP Pathway: Effects on Linaclotide-Induced Electrolyte Secretion and cGMP Efflux
Boris Tchernychev, Pei Ge, Marco M Kessler, et al.
Plos One
|
July 30, 2015
Linaclotide in Chronic Idiopathic Constipation Patients with Moderate to Severe Abdominal Bloating: A Randomized, Controlled Trial
Brian E Lacy, Ron Schey, Steven J Shiff, et al.
Journal of Medicinal Chemistry
|
April 5, 2002
Synthesis and biological characterization of L-N(6)-(1-iminoethyl)lysine 5-tetrazole-amide, a prodrug of a selective iNOS inhibitor
E Ann Hallinan, Sofya Tsymbalov, Clifford R Dorn, et al.
European Journal of Pharmacology
|
September 25, 2010
Linaclotide, through activation of guanylate cyclase C, acts locally in the gastrointestinal tract to elicit enhanced intestinal secretion and transit
Robert W Busby, Alexander P Bryant, Wilmin P Bartolini, et al.
Life Sciences
|
March 24, 2010
Linaclotide is a potent and selective guanylate cyclase C agonist that elicits pharmacological effects locally in the gastrointestinal tract
Alexander P Bryant, Robert W Busby, Wilmin P Bartolini, et al.
Journal of Gastroenterology and Hepatology
|
January 11, 2018
Linaclotide in irritable bowel syndrome with constipation: A Phase 3 randomized trial in China and other regions
Yunsheng Yang, Jingyuan Fang, Xiaozhong Guo, et al.
The American Journal of Gastroenterology
|
September 19, 2012
Linaclotide for irritable bowel syndrome with constipation: a 26-week, randomized, double-blind, placebo-controlled trial to evaluate efficacy and safety
William D Chey, Anthony J Lembo, Bernard J Lavins, et al.
Page
of 5