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Mark Holbrook

Showing results (1-10 of 16) with videos related to

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Journal of Pharmacological and Toxicological Methods|March 8, 2021
Strategies to encourage the adoption of social housing during cardiovascular telemetry recordings in non-rodentsHelen Prior, Mark Holbrook
Journal of Clinical Pharmacy and Therapeutics|September 6, 2022
Utilization of mechanistic modelling and simulation to analyse fenspiride proarrhythmic potency - Role of physiological and other non-drug related parametersBarbara Wiśniowska, Mark Holbrook, Christopher Pollard, et al.
Drug Discovery Today|May 28, 2019
Better prediction of the local concentration-effect relationship: the role of physiologically based pharmacokinetics and quantitative systems pharmacology and toxicology in the evolution of model-informed drug discovery and developmentSebastian Polak, Zofia Tylutki, Mark Holbrook, et al.
Journal of Pharmacological and Toxicological Methods|October 7, 2008
Drug induced shortening of the QT/QTc interval: an emerging safety issue warranting further modelling and evaluation in drug research and development?Mark Holbrook, Marek Malik, Rashmi R Shah, et al.
Journal of Pharmacological and Toxicological Methods|September 16, 2014
Measurement of hyper- and hypotension during repeated dose toxicity studies in either freely moving or physically restrained cynomolgus monkeysMarc O Niehoff, Birgit Niggemann, Jan Sternberg, et al.
Journal of Pharmacological and Toxicological Methods|May 21, 2013
Safety pharmacology investigations in toxicology studies: an industry surveySimon Authier, Hugo M Vargas, Michael J Curtis, et al.
Biochemical Pharmacology|November 22, 2005
Molecular cloning and radioligand binding characterization of the chemokine receptor CCR5 from rhesus macaque and humanCarolyn Napier, Harriet Sale, Michael Mosley, et al.
Veterinary Immunology and Immunopathology|June 30, 2006
The molecular cloning and functional expression of the dog CCR5Michael Mosley, Sarah Pullen, Andrew Botham, et al.
Journal of Pharmacological and Toxicological Methods|July 8, 2008
Zebrafish assays as early safety pharmacology screens: paradigm shift or red herring?William S Redfern, Gareth Waldron, Matthew J Winter, et al.
Journal of Pharmacological and Toxicological Methods|March 23, 2011
Pharmacokinetic-pharmacodynamic modelling of the effect of Moxifloxacin on QTc prolongation in telemetered cynomolgus monkeysKenny J Watson, William P Gorczyca, John Umland, et al.
Pageof 2

Showing results (1-10 of 16) with videos related to

Sort By:
Pageof 2
Journal of Pharmacological and Toxicological Methods|March 8, 2021
Strategies to encourage the adoption of social housing during cardiovascular telemetry recordings in non-rodentsHelen Prior, Mark Holbrook
Journal of Clinical Pharmacy and Therapeutics|September 6, 2022
Utilization of mechanistic modelling and simulation to analyse fenspiride proarrhythmic potency - Role of physiological and other non-drug related parametersBarbara Wiśniowska, Mark Holbrook, Christopher Pollard, et al.
Drug Discovery Today|May 28, 2019
Better prediction of the local concentration-effect relationship: the role of physiologically based pharmacokinetics and quantitative systems pharmacology and toxicology in the evolution of model-informed drug discovery and developmentSebastian Polak, Zofia Tylutki, Mark Holbrook, et al.
Journal of Pharmacological and Toxicological Methods|October 7, 2008
Drug induced shortening of the QT/QTc interval: an emerging safety issue warranting further modelling and evaluation in drug research and development?Mark Holbrook, Marek Malik, Rashmi R Shah, et al.
Journal of Pharmacological and Toxicological Methods|September 16, 2014
Measurement of hyper- and hypotension during repeated dose toxicity studies in either freely moving or physically restrained cynomolgus monkeysMarc O Niehoff, Birgit Niggemann, Jan Sternberg, et al.
Journal of Pharmacological and Toxicological Methods|May 21, 2013
Safety pharmacology investigations in toxicology studies: an industry surveySimon Authier, Hugo M Vargas, Michael J Curtis, et al.
Biochemical Pharmacology|November 22, 2005
Molecular cloning and radioligand binding characterization of the chemokine receptor CCR5 from rhesus macaque and humanCarolyn Napier, Harriet Sale, Michael Mosley, et al.
Veterinary Immunology and Immunopathology|June 30, 2006
The molecular cloning and functional expression of the dog CCR5Michael Mosley, Sarah Pullen, Andrew Botham, et al.
Journal of Pharmacological and Toxicological Methods|July 8, 2008
Zebrafish assays as early safety pharmacology screens: paradigm shift or red herring?William S Redfern, Gareth Waldron, Matthew J Winter, et al.
Journal of Pharmacological and Toxicological Methods|March 23, 2011
Pharmacokinetic-pharmacodynamic modelling of the effect of Moxifloxacin on QTc prolongation in telemetered cynomolgus monkeysKenny J Watson, William P Gorczyca, John Umland, et al.
Pageof 2