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Pharmaceutics|October 27, 2022
Optimization of a Novel Mandelamide-Derived Pyrrolopyrimidine Series of PERK InhibitorsMichael E Stokes, Matthew D Surman, Veronica Calvo, et al.
Future Medicinal Chemistry|March 24, 2011
Discovery of OSI-906: a selective and orally efficacious dual inhibitor of the IGF-1 receptor and insulin receptorMark J Mulvihill, Andrew Cooke, Maryland Rosenfeld-Franklin, et al.
Molecular Cancer Therapeutics|August 3, 2007
A novel, potent, and selective insulin-like growth factor-I receptor kinase inhibitor blocks insulin-like growth factor-I receptor signaling in vitro and inhibits insulin-like growth factor-I receptor dependent tumor growth in vivoQun-sheng Ji, Mark J Mulvihill, Maryland Rosenfeld-Franklin, et al.
Clinical Cancer Research : an Official Journal of the American Association for Cancer Research|September 21, 2023
PERK Inhibition by HC-5404 Sensitizes Renal Cell Carcinoma Tumor Models to Antiangiogenic Tyrosine Kinase InhibitorsMichael E Stokes, Veronica Calvo, Sho Fujisawa, et al.
ACS Medicinal Chemistry Letters|June 6, 2014
Discovery of novel insulin-like growth factor-1 receptor inhibitors with unique time-dependent binding kineticsMeizhong Jin, Brenda A Petronella, Andy Cooke, et al.
Bioorganic & Medicinal Chemistry Letters|January 16, 2013
Discovery of potent, selective and orally bioavailable imidazo[1,5-a]pyrazine derived ACK1 inhibitorsMeizhong Jin, Jing Wang, Andrew Kleinberg, et al.
Bioorganic & Medicinal Chemistry Letters|July 17, 2013
Discovery of 7-aminofuro[2,3-c]pyridine inhibitors of TAK1: optimization of kinase selectivity and pharmacokineticsKeith R Hornberger, Xin Chen, Andrew P Crew, et al.
Bioorganic & Medicinal Chemistry Letters|March 5, 2005
Potent and selective [2-imidazol-1-yl-2-(6-alkoxy-naphthalen-2-yl)-1-methyl-ethyl]-dimethyl-amines as retinoic acid metabolic blocking agents (RAMBAs)Mark J Mulvihill, Julie L C Kan, Patricia Beck, et al.
Bioorganic & Medicinal Chemistry Letters|January 22, 2011
Potent and selective cyclohexyl-derived imidazopyrazine insulin-like growth factor 1 receptor inhibitors with in vivo efficacyMeizhong Jin, Andrew Kleinberg, Andy Cooke, et al.
Organic & Biomolecular Chemistry|December 14, 2006
A highly effective one-pot synthesis of quinolines from o-nitroarylcarbaldehydesAn-Hu Li, Eilaf Ahmed, Xin Chen, et al.
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