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Nature Communications|April 10, 2020
Developing a new class of engineered live bacterial therapeutics to treat human diseasesMark R Charbonneau, Vincent M Isabella, Ning Li, et al.
Science (New York, N.Y.)|June 25, 2016
Childhood undernutrition, the gut microbiota, and microbiota-directed therapeuticsLaura V Blanton, Michael J Barratt, Mark R Charbonneau, et al.
International Journal of Molecular Sciences|July 28, 2026
A Defined Synbiotic Produces Immunomodulatory Metabolites, Engages Gut-Immune Pathways Relevant to Inflammaging, and Supports Healthy Aging in a Nematode ModelRyan S Green, Daniela Diaz-Infante Morales, Eric M Schott, et al.
Communications Biology|July 23, 2021
Development of a mechanistic model to predict synthetic biotic activity in healthy volunteers and patients with phenylketonuriaMark R Charbonneau, William S Denney, Nicholas G Horvath, et al.
Nature|July 8, 2016
A microbial perspective of human developmental biologyMark R Charbonneau, Laura V Blanton, Daniel B DiGiulio, et al.
Journal of Functional Foods|January 26, 2026
A synbiotic medical food improves gut barrier function, reduces immune responses, and inhibits osteoclast activity in models of postmenopausal bone loss aligned with clinical outcomesRyan S Green, Tyler Roy, Daniela Diaz-Infante Morales, et al.
Biorxiv : the Preprint Server for Biology|August 20, 2025
A synbiotic medical food improves gut barrier function, reduces immune responses, and inhibits osteoclast activity in models of postmenopausal bone loss aligned with clinical outcomesRyan S Green, Tyler Roy, Daniela Diaz-Infante Morales, et al.
Nature Communications|May 15, 2021
Characterization of an engineered live bacterial therapeutic for the treatment of phenylketonuria in a human gut-on-a-chipM Tyler Nelson, Mark R Charbonneau, Heidi G Coia, et al.
Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association|June 28, 2024
Food safety assessment and 28-day toxicity study of the synbiotic medical food consortium SBD121D Davidson Easson, Vincent A Murphy, Alicia E Ballok, et al.
Molecular Systems Biology|March 7, 2022
An engineered bacterial therapeutic lowers urinary oxalate in preclinical models and in silico simulations of enteric hyperoxaluriaDavid Lubkowicz, Nicholas G Horvath, Michael J James, et al.
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