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Trends in Cell Biology|February 23, 2010
The p53 orchestra: Mdm2 and Mdmx set the toneMark Wade, Yunyuan V Wang, Geoffrey M WahlCancer Cell|July 4, 2009
Increased radioresistance and accelerated B cell lymphomas in mice with Mdmx mutations that prevent modifications by DNA-damage-activated kinasesYunyuan V Wang, Mathias Leblanc, Mark Wade, et al.Proceedings of the National Academy of Sciences of the United States of America|July 21, 2007
Quantitative analyses reveal the importance of regulated Hdmx degradation for p53 activationYunyuan V Wang, Mark Wade, Eetsin Wong, et al.Molecular Cancer Research : MCR|January 17, 2009
Targeting Mdm2 and Mdmx in cancer therapy: better living through medicinal chemistry?Mark Wade, Geoffrey M WahlNature Reviews. Cancer|January 11, 2013
MDM2, MDMX and p53 in oncogenesis and cancer therapyMark Wade, Yao-Cheng Li, Geoffrey M WahlCell Cycle (Georgetown, Tex.)|July 8, 2008
BH3 activation blocks Hdmx suppression of apoptosis and cooperates with Nutlin to induce cell deathMark Wade, Luo Wei Rodewald, Joaquín M Espinosa, et al.The Journal of Biological Chemistry|May 5, 2012
Hypoxia activates tumor suppressor p53 by inducing ATR-Chk1 kinase cascade-mediated phosphorylation and consequent 14-3-3γ inactivation of MDMX proteinJun-Ho Lee, Yetao Jin, Guifen He, et al.The Journal of Biological Chemistry|August 15, 2006
Hdmx modulates the outcome of p53 activation in human tumor cellsMark Wade, Ee Tsin Wong, Mengjia Tang, et al.Nature|August 12, 2009
Linking the p53 tumour suppressor pathway to somatic cell reprogrammingTeruhisa Kawamura, Jotaro Suzuki, Yunyuan V Wang, et al.Molecular Cell|June 7, 2002
c-Myc can induce DNA damage, increase reactive oxygen species, and mitigate p53 function: a mechanism for oncogene-induced genetic instabilityOmid Vafa, Mark Wade, Suzanne Kern, et al.Pageof 21