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Alzheimer'S Research & Therapy|January 5, 2021
The molecular tweezer CLR01 improves behavioral deficits and reduces tau pathology in P301S-tau transgenic miceJing Di, Ibrar Siddique, Zizheng Li, et al.Chemistry (Weinheim an Der Bergstrasse, Germany)|July 3, 2024
Functional Linkers Support Targeting of Multivalent Tweezers to Taspase1Katrin Hommel, Alisa-Maite A Kauth, Abbna Kirupakaran, et al.Molecular Therapy : the Journal of the American Society of Gene Therapy|February 23, 2020
The Amyloid Inhibitor CLR01 Relieves Autophagy and Ameliorates Neuropathology in a Severe Lysosomal Storage DiseaseAntonio Monaco, Veronica Maffia, Nicolina Cristina Sorrentino, et al.Neurotherapeutics : the Journal of the American Society for Experimental Neurotherapeutics|March 1, 2012
A novel "molecular tweezer" inhibitor of α-synuclein neurotoxicity in vitro and in vivoShubhangi Prabhudesai, Sharmistha Sinha, Aida Attar, et al.ACS Chemical Biology|April 7, 2015
Molecular tweezers inhibit islet amyloid polypeptide assembly and toxicity by a new mechanismDahabada H J Lopes, Aida Attar, Gayatri Nair, et al.Biochimica Et Biophysica Acta. Molecular Basis of Disease|July 19, 2019
The molecular tweezer CLR01 reduces aggregated, pathologic, and seeding-competent α-synuclein in experimental multiple system atrophyMarcos Herrera-Vaquero, Danielle Bouquio, Martin Kallab, et al.Cell Chemical Biology|April 14, 2021
Inhibition of Staphylococcus aureus biofilm-forming functional amyloid by molecular tweezersRavit Malishev, Nir Salinas, James Gibson, et al.Neurotherapeutics : the Journal of the American Society for Experimental Neurotherapeutics|June 7, 2017
A Molecular Tweezer Ameliorates Motor Deficits in Mice Overexpressing α-SynucleinFranziska Richter, Sudhakar R Subramaniam, Iddo Magen, et al.Nature Communications|March 9, 2021
Specific inhibition of the Survivin-CRM1 interaction by peptide-modified molecular tweezersAnnika Meiners, Sandra Bäcker, Inesa Hadrović, et al.Nature Communications|June 16, 2018
Cell entry of a host-targeting protein of oomycetes requires gp96Franziska Trusch, Lars Loebach, Stephan Wawra, et al.Pageof 16