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Bioorganic & Medicinal Chemistry Letters
|
September 18, 2013
Design and evaluation of novel 8-oxo-pyridopyrimidine Jak1/2 inhibitors
Sharada Labadie, Kathy Barrett, Wade S Blair, et al.
The Journal of Allergy and Clinical Immunology
|
March 21, 2021
Inhaled JAK inhibitor GDC-0214 reduces exhaled nitric oxide in patients with mild asthma: A randomized, controlled, proof-of-activity trial
Irene E Braithwaite, Fang Cai, Jennifer A Tom, et al.
Toxicological Sciences : an Official Journal of the Society of Toxicology
|
December 16, 2014
Retinal toxicity, in vivo and in vitro, associated with inhibition of nicotinamide phosphoribosyltransferase
Tanja S Zabka, Jatinder Singh, Preeti Dhawan, et al.
Bioorganic & Medicinal Chemistry Letters
|
August 1, 2013
Identification of 2,3-dihydro-1H-pyrrolo[3,4-c]pyridine-derived ureas as potent inhibitors of human nicotinamide phosphoribosyltransferase (NAMPT)
Peter S Dragovich, Kenneth W Bair, Timm Baumeister, et al.
Journal of Medicinal Chemistry
|
August 20, 2016
Minimizing CYP2C9 Inhibition of Exposed-Pyridine NAMPT (Nicotinamide Phosphoribosyltransferase) Inhibitors
Mark Zak, Po-Wai Yuen, Xiongcai Liu, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals
|
July 4, 2019
Drug Concentration Asymmetry in Tissues and Plasma for Small Molecule-Related Therapeutic Modalities
Donglu Zhang, Cornelis E C A Hop, Gabriela Patilea-Vrana, et al.
Bioorganic & Medicinal Chemistry Letters
|
January 18, 2014
Fragment-based design of 3-aminopyridine-derived amides as potent inhibitors of human nicotinamide phosphoribosyltransferase (NAMPT)
Peter S Dragovich, Guiling Zhao, Timm Baumeister, et al.
Bioorganic & Medicinal Chemistry Letters
|
November 28, 2013
Discovery of potent and efficacious cyanoguanidine-containing nicotinamide phosphoribosyltransferase (Nampt) inhibitors
Xiaozhang Zheng, Timm Baumeister, Alexandre J Buckmelter, et al.
Nature
|
August 13, 2013
Mechanism of MEK inhibition determines efficacy in mutant KRAS- versus BRAF-driven cancers
Georgia Hatzivassiliou, Jacob R Haling, Huifen Chen, et al.
Journal of Medicinal Chemistry
|
April 27, 2013
Structure-based identification of ureas as novel nicotinamide phosphoribosyltransferase (Nampt) inhibitors
Xiaozhang Zheng, Paul Bauer, Timm Baumeister, et al.
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Showing results (11-20 of 34) with videos related to
Sort By:
Page
of 4
Bioorganic & Medicinal Chemistry Letters
|
September 18, 2013
Design and evaluation of novel 8-oxo-pyridopyrimidine Jak1/2 inhibitors
Sharada Labadie, Kathy Barrett, Wade S Blair, et al.
The Journal of Allergy and Clinical Immunology
|
March 21, 2021
Inhaled JAK inhibitor GDC-0214 reduces exhaled nitric oxide in patients with mild asthma: A randomized, controlled, proof-of-activity trial
Irene E Braithwaite, Fang Cai, Jennifer A Tom, et al.
Toxicological Sciences : an Official Journal of the Society of Toxicology
|
December 16, 2014
Retinal toxicity, in vivo and in vitro, associated with inhibition of nicotinamide phosphoribosyltransferase
Tanja S Zabka, Jatinder Singh, Preeti Dhawan, et al.
Bioorganic & Medicinal Chemistry Letters
|
August 1, 2013
Identification of 2,3-dihydro-1H-pyrrolo[3,4-c]pyridine-derived ureas as potent inhibitors of human nicotinamide phosphoribosyltransferase (NAMPT)
Peter S Dragovich, Kenneth W Bair, Timm Baumeister, et al.
Journal of Medicinal Chemistry
|
August 20, 2016
Minimizing CYP2C9 Inhibition of Exposed-Pyridine NAMPT (Nicotinamide Phosphoribosyltransferase) Inhibitors
Mark Zak, Po-Wai Yuen, Xiongcai Liu, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals
|
July 4, 2019
Drug Concentration Asymmetry in Tissues and Plasma for Small Molecule-Related Therapeutic Modalities
Donglu Zhang, Cornelis E C A Hop, Gabriela Patilea-Vrana, et al.
Bioorganic & Medicinal Chemistry Letters
|
January 18, 2014
Fragment-based design of 3-aminopyridine-derived amides as potent inhibitors of human nicotinamide phosphoribosyltransferase (NAMPT)
Peter S Dragovich, Guiling Zhao, Timm Baumeister, et al.
Bioorganic & Medicinal Chemistry Letters
|
November 28, 2013
Discovery of potent and efficacious cyanoguanidine-containing nicotinamide phosphoribosyltransferase (Nampt) inhibitors
Xiaozhang Zheng, Timm Baumeister, Alexandre J Buckmelter, et al.
Nature
|
August 13, 2013
Mechanism of MEK inhibition determines efficacy in mutant KRAS- versus BRAF-driven cancers
Georgia Hatzivassiliou, Jacob R Haling, Huifen Chen, et al.
Journal of Medicinal Chemistry
|
April 27, 2013
Structure-based identification of ureas as novel nicotinamide phosphoribosyltransferase (Nampt) inhibitors
Xiaozhang Zheng, Paul Bauer, Timm Baumeister, et al.
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of 4