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Journal of Immunology (Baltimore, Md. : 1950)
|
July 30, 2013
A restricted role for TYK2 catalytic activity in human cytokine responses revealed by novel TYK2-selective inhibitors
Sue J Sohn, Kathy Barrett, Anne Van Abbema, et al.
Bioorganic & Medicinal Chemistry Letters
|
October 31, 2012
Structure-based discovery of C-2 substituted imidazo-pyrrolopyridine JAK1 inhibitors with improved selectivity over JAK2
Sharada Labadie, Peter S Dragovich, Kathy Barrett, et al.
Bioorganic & Medicinal Chemistry Letters
|
May 7, 2013
Novel triazolo-pyrrolopyridines as inhibitors of Janus kinase 1
Christopher A Hurley, Wade S Blair, Richard J Bull, et al.
Journal of Medicinal Chemistry
|
July 18, 2013
Structure-based discovery of novel amide-containing nicotinamide phosphoribosyltransferase (nampt) inhibitors
Xiaozhang Zheng, Paul Bauer, Timm Baumeister, et al.
Journal of Medicinal Chemistry
|
January 11, 2014
Fragment-based identification of amides derived from trans-2-(pyridin-3-yl)cyclopropanecarboxylic acid as potent inhibitors of human nicotinamide phosphoribosyltransferase (NAMPT)
Anthony M Giannetti, Xiaozhang Zheng, Nicholas J Skelton, et al.
Bioorganic & Medicinal Chemistry Letters
|
January 4, 2015
Identification of nicotinamide phosphoribosyltransferase (NAMPT) inhibitors with no evidence of CYP3A4 time-dependent inhibition and improved aqueous solubility
Mark Zak, Bianca M Liederer, Deepak Sampath, et al.
ACS Central Science
|
October 3, 2022
Correction to "An Iterative Approach Guides Discovery of the FabI Inhibitor Fabimycin, a Late-Stage Antibiotic Candidate with <i>In Vivo</i> Efficacy against Drug-Resistant Gram-Negative Infections"
Erica N Parker, Brett N Cain, Behnoush Hajian, et al.
Bioorganic & Medicinal Chemistry Letters
|
April 15, 2019
Discovery of a class of highly potent Janus Kinase 1/2 (JAK1/2) inhibitors demonstrating effective cell-based blockade of IL-13 signaling
Mark Zak, Emily J Hanan, Patrick Lupardus, et al.
Journal of Medicinal Chemistry
|
May 18, 2012
Identification of imidazo-pyrrolopyridines as novel and potent JAK1 inhibitors
Janusz J Kulagowski, Wade Blair, Richard J Bull, et al.
Science Translational Medicine
|
November 23, 2018
Lung-restricted inhibition of Janus kinase 1 is effective in rodent models of asthma
Hart S Dengler, Xiumin Wu, Ivan Peng, et al.
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Search research articles
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Showing results (21-30 of 34) with videos related to
Sort By:
Page
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Journal of Immunology (Baltimore, Md. : 1950)
|
July 30, 2013
A restricted role for TYK2 catalytic activity in human cytokine responses revealed by novel TYK2-selective inhibitors
Sue J Sohn, Kathy Barrett, Anne Van Abbema, et al.
Bioorganic & Medicinal Chemistry Letters
|
October 31, 2012
Structure-based discovery of C-2 substituted imidazo-pyrrolopyridine JAK1 inhibitors with improved selectivity over JAK2
Sharada Labadie, Peter S Dragovich, Kathy Barrett, et al.
Bioorganic & Medicinal Chemistry Letters
|
May 7, 2013
Novel triazolo-pyrrolopyridines as inhibitors of Janus kinase 1
Christopher A Hurley, Wade S Blair, Richard J Bull, et al.
Journal of Medicinal Chemistry
|
July 18, 2013
Structure-based discovery of novel amide-containing nicotinamide phosphoribosyltransferase (nampt) inhibitors
Xiaozhang Zheng, Paul Bauer, Timm Baumeister, et al.
Journal of Medicinal Chemistry
|
January 11, 2014
Fragment-based identification of amides derived from trans-2-(pyridin-3-yl)cyclopropanecarboxylic acid as potent inhibitors of human nicotinamide phosphoribosyltransferase (NAMPT)
Anthony M Giannetti, Xiaozhang Zheng, Nicholas J Skelton, et al.
Bioorganic & Medicinal Chemistry Letters
|
January 4, 2015
Identification of nicotinamide phosphoribosyltransferase (NAMPT) inhibitors with no evidence of CYP3A4 time-dependent inhibition and improved aqueous solubility
Mark Zak, Bianca M Liederer, Deepak Sampath, et al.
ACS Central Science
|
October 3, 2022
Correction to "An Iterative Approach Guides Discovery of the FabI Inhibitor Fabimycin, a Late-Stage Antibiotic Candidate with <i>In Vivo</i> Efficacy against Drug-Resistant Gram-Negative Infections"
Erica N Parker, Brett N Cain, Behnoush Hajian, et al.
Bioorganic & Medicinal Chemistry Letters
|
April 15, 2019
Discovery of a class of highly potent Janus Kinase 1/2 (JAK1/2) inhibitors demonstrating effective cell-based blockade of IL-13 signaling
Mark Zak, Emily J Hanan, Patrick Lupardus, et al.
Journal of Medicinal Chemistry
|
May 18, 2012
Identification of imidazo-pyrrolopyridines as novel and potent JAK1 inhibitors
Janusz J Kulagowski, Wade Blair, Richard J Bull, et al.
Science Translational Medicine
|
November 23, 2018
Lung-restricted inhibition of Janus kinase 1 is effective in rodent models of asthma
Hart S Dengler, Xiumin Wu, Ivan Peng, et al.
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of 4