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Molecular Biosystems|August 10, 2016
Panels of chemically-modified heparin polysaccharides and natural heparan sulfate saccharides both exhibit differences in binding to Slit and Robo, as well as variation between protein binding and cellular activityYassir A Ahmed, Edwin A Yates, Diana J Moss, et al.
Molecular Immunology|September 24, 2014
The role of heparan sulfate as determining pathogenic factor in complement factor H-associated diseasesMarkus A Loeven, Angelique L W M M Rops, Jo H M Berden, et al.
Plos One|November 30, 2016
RNA Contaminates Glycosaminoglycans Extracted from Cells and TissuesJasper J van Gemst, Markus A Loeven, Mark J J de Graaf, et al.
Investigative Ophthalmology & Visual Science|February 3, 2018
A Novel Choroidal Endothelial Cell Line Has a Decreased Affinity for the Age-Related Macular Degeneration-Associated Complement Factor H Variant 402HMarkus A Loeven, Jasper J van Gemst, Carolien M S Schophuizen, et al.
Plos One|December 23, 2021
Blocking of inflammatory heparan sulfate domains by specific antibodies is not protective in experimental glomerulonephritisJasper J van Gemst, Nathalie J H G Passmann, Angelique L W M M Rops, et al.
Frontiers in Immunology|September 7, 2021
Selective Binding of Heparin/Heparan Sulfate Oligosaccharides to Factor H and Factor H-Related Proteins: Therapeutic Potential for C3 GlomerulopathiesMarkus A Loeven, Marissa L Maciej-Hulme, Cansu Yanginlar, et al.
The Journal of Biological Chemistry|January 6, 2016
Mutations in Complement Factor H Impair Alternative Pathway Regulation on Mouse Glomerular Endothelial Cells in VitroMarkus A Loeven, Angelique L Rops, Markus J Lehtinen, et al.
Scientific Reports|May 24, 2020
Inhibition of mTOR delayed but could not prevent experimental collapsing focal segmental glomerulosclerosisLaura Miesen, Jennifer Eymael, Shagun Sharma, et al.
Arteriosclerosis, Thrombosis, and Vascular Biology|May 13, 2017
Neutrophil Extracellular Traps Drive Endothelial-to-Mesenchymal TransitionElmar Pieterse, Nils Rother, Marjolein Garsen, et al.
Kidney International|April 25, 2014
Modulation of heparan sulfate in the glomerular endothelial glycocalyx decreases leukocyte influx during experimental glomerulonephritisAngelique L W M M Rops, Markus A Loeven, Jasper J van Gemst, et al.
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