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Bioorganic & Medicinal Chemistry Letters|January 23, 2013
Discovery of 5-phenoxy-1,3-dimethyl-1H-pyrazole-4-carboxamides as potent agonists of TGR5 via sequential combinatorial librariesAllyn T Londregan, David W Piotrowski, Kentaro Futatsugi, et al.ACS Medicinal Chemistry Letters|January 21, 2022
Discovery of Small-Molecule CD33 Pre-mRNA Splicing ModulatorsThomas A Chappie, Mario Abdelmessih, Claude W Ambroise, et al.Cell Chemical Biology|October 18, 2016
A Small-Molecule Anti-secretagogue of PCSK9 Targets the 80S Ribosome to Inhibit PCSK9 Protein TranslationDonna N Petersen, Julie Hawkins, Wanida Ruangsiriluk, et al.ACS Medicinal Chemistry Letters|May 26, 2018
Discovery of Orally Bioavailable Selective Inhibitors of the Sodium-Phosphate Cotransporter NaPi2a (SLC34A1)Kevin J Filipski, Matthew F Sammons, Samit K Bhattacharya, et al.ACS Medicinal Chemistry Letters|February 20, 2018
Discovery and in Vitro Optimization of 3-Sulfamoylbenzamides as ROMK InhibitorsMatthew F Sammons, Sujay V Kharade, Kevin J Filipski, et al.Clinical Cancer Research : an Official Journal of the American Association for Cancer Research|October 13, 2016
Preclinical Therapeutic Synergy of MEK1/2 and CDK4/6 Inhibition in NeuroblastomaLori S Hart, JulieAnn Rader, Pichai Raman, et al.Plos One|June 16, 2015
Patterns of HER2 Gene Amplification and Response to Anti-HER2 TherapiesRocio Vicario, Vicente Peg, Beatriz Morancho, et al.The Journal of Biological Chemistry|November 15, 2025
Discovery of small molecule modulators of the thin filament that alter the contractile profile in a hypertrophic cardiomyopathy engineered tissue modelRuth F Sommese, Samuel M Levi, Janice Brown, et al.Clinical Cancer Research : an Official Journal of the American Association for Cancer Research|December 18, 2015
Personalized Preclinical Trials in BRAF Inhibitor-Resistant Patient-Derived Xenograft Models Identify Second-Line Combination TherapiesClemens Krepler, Min Xiao, Katrin Sproesser, et al.ACS Medicinal Chemistry Letters|June 6, 2014
Chemical Probe Identification Platform for Orphan GPCRs Using Focused Compound Screening: GPR39 as a Case ExampleMarkus Boehm, David Hepworth, Paula M Loria, et al.Pageof 4