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Cell Reports|October 19, 2022
A systemic cell stress signal confers neuronal resilience toward oxidative stress in a Hedgehog-dependent mannerKyung Min Chung, Hyunha Kim, Cláudio Gouveia Roque, et al.Journal of Neuro-Oncology|December 19, 2023
MGMT promoter methylation in 1p19q-intact gliomasConnor J Kinslow, Markus D Siegelin, Fabio M Iwamoto, et al.The Journal of Clinical Investigation|March 3, 2011
Exploiting the mitochondrial unfolded protein response for cancer therapy in mice and human cellsMarkus D Siegelin, Takehiko Dohi, Christopher M Raskett, et al.Molecular Oncology|April 3, 2024
The Alcatraz-Strategy: a roadmap to break the connectivity barrier in malignant brain tumoursMatthias Schneider, Anna-Laura Potthoff, Georg Karpel-Massler, et al.Plos One|December 23, 2014
PARP inhibition restores extrinsic apoptotic sensitivity in glioblastomaGeorg Karpel-Massler, Fresia Pareja, Pascaline Aimé, et al.Clinical Cancer Research : an Official Journal of the American Association for Cancer Research|April 30, 2016
A Synthetic Cell-Penetrating Dominant-Negative ATF5 Peptide Exerts Anticancer Activity against a Broad Spectrum of Treatment-Resistant CancersGeorg Karpel-Massler, Basil A Horst, Chang Shu, et al.Scientific Reports|May 11, 2018
Inhibition of Bcl-2/Bcl-xL and c-MET causes synthetic lethality in model systems of glioblastomaYiru Zhang, Chiaki Tsuge Ishida, Chang Shu, et al.Neurochemical Research|August 31, 2017
Anti-glioma Activity of Dapsone and Its Enhancement by Synthetic Chemical ModificationGeorg Karpel-Massler, Richard E Kast, Markus D Siegelin, et al.Cellular Oncology (Dordrecht, Netherlands)|March 13, 2019
Combined inhibition of RAC1 and Bcl-2/Bcl-xL synergistically induces glioblastoma cell death through down-regulation of the Usp9X/Mcl-1 axisMichal Hlavac, Annika Dwucet, Richard Eric Kast, et al.Oncotarget|May 27, 2015
Combined inhibition of Bcl-2/Bcl-xL and Usp9X/Bag3 overcomes apoptotic resistance in glioblastoma in vitro and in vivoGeorg Karpel-Massler, Chang Shu, Lily Chau, et al.Pageof 9