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Journal of Medicinal Chemistry|June 15, 2018
Computer-Assisted Discovery of Retinoid X Receptor Modulating Natural Products and Isofunctional MimeticsDaniel Merk, Francesca Grisoni, Lukas Friedrich, et al.
Bioorganic & Medicinal Chemistry|July 21, 2018
Structural optimization and in vitro profiling of N-phenylbenzamide-based farnesoid X receptor antagonistsJurema Schmidt, Simone Schierle, Leonie Gellrich, et al.
The Journal of Biological Chemistry|June 3, 2021
Heterodimer formation with retinoic acid receptor RXRα modulates coactivator recruitment by peroxisome proliferator-activated receptor PPARγWhitney Kilu, Daniel Merk, Dieter Steinhilber, et al.
Chemistryopen|January 10, 2019
Discovery of Novel Molecular Frameworks of Farnesoid X Receptor Modulators by Ensemble Machine LearningDaniel Merk, Francesca Grisoni, Kay Schaller, et al.
RSC Medicinal Chemistry|August 18, 2025
Fragment-based discovery of dual ligand pharmacophores for lipid-sensing transcription factors for designed polypharmacologyTanja Stiller, Silke Duensing-Kropp, Julian A Marschner, et al.
Angewandte Chemie (International Ed. in English)|June 24, 2021
Beam Search for Automated Design and Scoring of Novel ROR Ligands with Machine Intelligence*Michael Moret, Moritz Helmstädter, Francesca Grisoni, et al.
Journal of Medicinal Chemistry|July 2, 2021
A Photohormone for Light-Dependent Control of PPARα in Live CellsSabine Willems, Johannes Morstein, Konstantin Hinnah, et al.
Medchemcomm|August 29, 2018
Scaffold hopping from synthetic RXR modulators by virtual screening and de novo designDaniel Merk, Francesca Grisoni, Lukas Friedrich, et al.
Chemmedchem|January 18, 2024
Rational design and virtual screening identify mimetics of the RXR agonist valerenic acidLaura Isigkeit, Annette Kärcher, Gustave Adouvi, et al.
Chemmedchem|June 15, 2022
Druggability Evaluation of the Neuron Derived Orphan Receptor (NOR-1) Reveals Inverse NOR-1 AgonistsDaniel Zaienne, Silvia Arifi, Julian A Marschner, et al.
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