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Journal of Medicinal Chemistry
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August 3, 2018
Mathematical and Structural Characterization of Strong Nonadditive Structure-Activity Relationship Caused by Protein Conformational Changes
Laurent Gomez, Rui Xu, William Sinko, et al.
Journal of the American Chemical Society
|
September 28, 2011
Prospective CCR5 small molecule antagonist compound design using a combined mutagenesis/modeling approach
Markus Metz, Elyse Bourque, Jean Labrecque, et al.
Virology
|
March 11, 2011
HIV-1 entry inhibition by small-molecule CCR5 antagonists: a combined molecular modeling and mutant study using a high-throughput assay
Jean Labrecque, Markus Metz, Gloria Lau, et al.
Bioorganic & Medicinal Chemistry Letters
|
April 22, 2011
The discovery of novel benzofuran-2-carboxylic acids as potent Pim-1 inhibitors
Yibin Xiang, Bradford Hirth, Gary Asmussen, et al.
Journal of Medicinal Chemistry
|
January 2, 2010
Synthesis and structure-activity relationships of azamacrocyclic C-X-C chemokine receptor 4 antagonists: analogues containing a single azamacrocyclic ring are potent inhibitors of T-cell tropic (X4) HIV-1 replication
Gary J Bridger, Renato T Skerlj, Pedro E Hernandez-Abad, et al.
Bioorganic & Medicinal Chemistry Letters
|
March 15, 2011
Design and synthesis of pyridin-2-yloxymethylpiperidin-1-ylbutyl amide CCR5 antagonists that are potent inhibitors of M-tropic (R5) HIV-1 replication
Renato Skerlj, Gary Bridger, Yuanxi Zhou, et al.
Journal of Medicinal Chemistry
|
February 21, 2012
Implications of promiscuous Pim-1 kinase fragment inhibitor hydrophobic interactions for fragment-based drug design
Andrew C Good, Jinyu Liu, Bradford Hirth, et al.
ACS Medicinal Chemistry Letters
|
June 6, 2014
Mitigating hERG Inhibition: Design of Orally Bioavailable CCR5 Antagonists as Potent Inhibitors of R5 HIV-1 Replication
Renato Skerlj, Gary Bridger, Yuanxi Zhou, et al.
ACS Medicinal Chemistry Letters
|
May 15, 2024
Identification of Selective Imidazopyridine CSF1R Inhibitors
John L Kane, Gary Asmussen, Joseph Batchelor, et al.
Scientific Data
|
August 2, 2016
Serial femtosecond crystallography datasets from G protein-coupled receptors
Thomas A White, Anton Barty, Wei Liu, et al.
Page
of 5
Search research articles
Search
Showing results (21-30 of 45) with videos related to
Sort By:
Page
of 5
Journal of Medicinal Chemistry
|
August 3, 2018
Mathematical and Structural Characterization of Strong Nonadditive Structure-Activity Relationship Caused by Protein Conformational Changes
Laurent Gomez, Rui Xu, William Sinko, et al.
Journal of the American Chemical Society
|
September 28, 2011
Prospective CCR5 small molecule antagonist compound design using a combined mutagenesis/modeling approach
Markus Metz, Elyse Bourque, Jean Labrecque, et al.
Virology
|
March 11, 2011
HIV-1 entry inhibition by small-molecule CCR5 antagonists: a combined molecular modeling and mutant study using a high-throughput assay
Jean Labrecque, Markus Metz, Gloria Lau, et al.
Bioorganic & Medicinal Chemistry Letters
|
April 22, 2011
The discovery of novel benzofuran-2-carboxylic acids as potent Pim-1 inhibitors
Yibin Xiang, Bradford Hirth, Gary Asmussen, et al.
Journal of Medicinal Chemistry
|
January 2, 2010
Synthesis and structure-activity relationships of azamacrocyclic C-X-C chemokine receptor 4 antagonists: analogues containing a single azamacrocyclic ring are potent inhibitors of T-cell tropic (X4) HIV-1 replication
Gary J Bridger, Renato T Skerlj, Pedro E Hernandez-Abad, et al.
Bioorganic & Medicinal Chemistry Letters
|
March 15, 2011
Design and synthesis of pyridin-2-yloxymethylpiperidin-1-ylbutyl amide CCR5 antagonists that are potent inhibitors of M-tropic (R5) HIV-1 replication
Renato Skerlj, Gary Bridger, Yuanxi Zhou, et al.
Journal of Medicinal Chemistry
|
February 21, 2012
Implications of promiscuous Pim-1 kinase fragment inhibitor hydrophobic interactions for fragment-based drug design
Andrew C Good, Jinyu Liu, Bradford Hirth, et al.
ACS Medicinal Chemistry Letters
|
June 6, 2014
Mitigating hERG Inhibition: Design of Orally Bioavailable CCR5 Antagonists as Potent Inhibitors of R5 HIV-1 Replication
Renato Skerlj, Gary Bridger, Yuanxi Zhou, et al.
ACS Medicinal Chemistry Letters
|
May 15, 2024
Identification of Selective Imidazopyridine CSF1R Inhibitors
John L Kane, Gary Asmussen, Joseph Batchelor, et al.
Scientific Data
|
August 2, 2016
Serial femtosecond crystallography datasets from G protein-coupled receptors
Thomas A White, Anton Barty, Wei Liu, et al.
Page
of 5