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Journal of Medicinal Chemistry
|
December 26, 2008
Metabolic soft spot identification and compound optimization in early discovery phases using MetaSite and LC-MS/MS validation
Markus Trunzer, Bernard Faller, Alfred Zimmerlin
Rapid Communications in Mass Spectrometry : RCM
|
February 14, 2007
Comparison of a two-dimensional liquid chromatography/mass spectrometry approach with a chip-based nanoelectrospray device for structural elucidation of metabolites in a human ADME study using a quadrupole time-of-flight mass spectrometer
Markus Trunzer, Daniel Graf, Michael Kiffe
Rapid Communications in Mass Spectrometry : RCM
|
February 15, 2007
Two-dimensional liquid chromatography/mass spectrometry set-up for structural elucidation of metabolites in complex biological matrices
Michael Kiffe, Daniel Graf, Markus Trunzer
Drug Metabolism and Disposition: the Biological Fate of Chemicals
|
March 9, 2011
CYP3A time-dependent inhibition risk assessment validated with 400 reference drugs
Alfred Zimmerlin, Markus Trunzer, Bernard Faller
Journal of Chromatography. A
|
May 1, 2007
Cytostar-T plates--a valid alternative for microplate scintillation counting of low radioactivity in combination with high-performance liquid chromatography in drug metabolism studies?
Michael Kiffe, Robert Nufer, Markus Trunzer, et al.
Chemical Research in Toxicology
|
March 19, 2024
Deep Learning Models Compared to Experimental Variability for the Prediction of CYP3A4 Time-Dependent Inhibition
Andrin Fluetsch, Markus Trunzer, Grégori Gerebtzoff, et al.
Molecular Pharmaceutics
|
November 28, 2022
Multispecies Machine Learning Predictions of In Vitro Intrinsic Clearance with Uncertainty Quantification Analyses
Raquel Rodríguez-Pérez, Markus Trunzer, Nadine Schneider, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals
|
February 15, 2024
Improving In Vitro-In Vivo Extrapolation of Clearance Using Rat Liver Microsomes for Highly Plasma Protein-Bound Molecules
Markus Trunzer, Joana Teigão, Felix Huth, et al.
Journal of Mass Spectrometry : JMS
|
February 3, 2017
Evaluation of relative MS response factors of drug metabolites for semi-quantitative assessment of chemical liabilities in drug discovery
Joachim Blanz, Gareth Williams, Jerôme Dayer, et al.
Journal of Medicinal Chemistry
|
October 31, 2023
Design of a Supersoft Topical JAK Inhibitor, Which Is Effective in Human Skin but Rapidly Deactivated in Blood
Gebhard Thoma, Odile Decoret, Eric Vangrevelinghe, et al.
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Search research articles
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Showing results (1-10 of 13) with videos related to
Sort By:
Page
of 2
Journal of Medicinal Chemistry
|
December 26, 2008
Metabolic soft spot identification and compound optimization in early discovery phases using MetaSite and LC-MS/MS validation
Markus Trunzer, Bernard Faller, Alfred Zimmerlin
Rapid Communications in Mass Spectrometry : RCM
|
February 14, 2007
Comparison of a two-dimensional liquid chromatography/mass spectrometry approach with a chip-based nanoelectrospray device for structural elucidation of metabolites in a human ADME study using a quadrupole time-of-flight mass spectrometer
Markus Trunzer, Daniel Graf, Michael Kiffe
Rapid Communications in Mass Spectrometry : RCM
|
February 15, 2007
Two-dimensional liquid chromatography/mass spectrometry set-up for structural elucidation of metabolites in complex biological matrices
Michael Kiffe, Daniel Graf, Markus Trunzer
Drug Metabolism and Disposition: the Biological Fate of Chemicals
|
March 9, 2011
CYP3A time-dependent inhibition risk assessment validated with 400 reference drugs
Alfred Zimmerlin, Markus Trunzer, Bernard Faller
Journal of Chromatography. A
|
May 1, 2007
Cytostar-T plates--a valid alternative for microplate scintillation counting of low radioactivity in combination with high-performance liquid chromatography in drug metabolism studies?
Michael Kiffe, Robert Nufer, Markus Trunzer, et al.
Chemical Research in Toxicology
|
March 19, 2024
Deep Learning Models Compared to Experimental Variability for the Prediction of CYP3A4 Time-Dependent Inhibition
Andrin Fluetsch, Markus Trunzer, Grégori Gerebtzoff, et al.
Molecular Pharmaceutics
|
November 28, 2022
Multispecies Machine Learning Predictions of In Vitro Intrinsic Clearance with Uncertainty Quantification Analyses
Raquel Rodríguez-Pérez, Markus Trunzer, Nadine Schneider, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals
|
February 15, 2024
Improving In Vitro-In Vivo Extrapolation of Clearance Using Rat Liver Microsomes for Highly Plasma Protein-Bound Molecules
Markus Trunzer, Joana Teigão, Felix Huth, et al.
Journal of Mass Spectrometry : JMS
|
February 3, 2017
Evaluation of relative MS response factors of drug metabolites for semi-quantitative assessment of chemical liabilities in drug discovery
Joachim Blanz, Gareth Williams, Jerôme Dayer, et al.
Journal of Medicinal Chemistry
|
October 31, 2023
Design of a Supersoft Topical JAK Inhibitor, Which Is Effective in Human Skin but Rapidly Deactivated in Blood
Gebhard Thoma, Odile Decoret, Eric Vangrevelinghe, et al.
Page
of 2