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Proceedings of the National Academy of Sciences of the United States of America|April 28, 2026
Restoring the 14-3-3/CRAF regulatory interaction in Noonan syndrome using molecular gluesJohanna M Virta, Holly R Vickery, Markella Konstantinidou, et al.
Angewandte Chemie (International Ed. in English)|December 19, 2025
Macrocyclic Molecular Glues for the 14-3-3/ChREBP Interaction: Affinity and Cooperativity in an Inverse RelationshipMarloes A M Pennings, Merel A W van den Bosch, Ansgar Oberheide, et al.
Chemical Science|November 25, 2022
Functional mapping of the 14-3-3 hub protein as a guide to design 14-3-3 molecular gluesBente A Somsen, Fenna W B Craenmehr, Wei-Hong W Liu, et al.
Nature Communications|March 2, 2025
Molecular glues of the regulatory ChREBP/14-3-3 complex protect beta cells from glucolipotoxicityLiora S Katz, Emira J Visser, Kathrin F Plitzko, et al.
Biorxiv : the Preprint Server for Biology|February 26, 2024
Molecular glues of the regulatory ChREBP/14-3-3 complex protect beta cells from glucolipotoxicityLiora S Katz, Emira J Visser, Kathrin F Plitzko, et al.
Nature Communications|July 14, 2025
Scaffold-hopping for molecular glues targeting the 14-3-3/ERα complexMarkella Konstantinidou, Marios Zingiridis, Marloes A M Pennings, et al.
Angewandte Chemie (International Ed. in English)|July 16, 2023
From Tethered to Freestanding Stabilizers of 14-3-3 Protein-Protein Interactions through Fragment LinkingEmira J Visser, Priyadarshini Jaishankar, Eline Sijbesma, et al.
Biorxiv : the Preprint Server for Biology|August 6, 2025
Modulation of the 14-3-3σ/C-RAF "auto"inhibited complex by molecular gluesMarkella Konstantinidou, Holly R Vickery, Marloes A M Pennings, et al.
Journal of the American Chemical Society|January 30, 2026
Modulation of the 14-3-3σ/C-RAF "Auto"inhibited Complex by Molecular GluesMarkella Konstantinidou, Holly R Vickery, Marloes A M Pennings, et al.
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