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Frontiers in Pharmacology|December 19, 2018
A Comparative Study on the Efficacy of NLRP3 Inflammasome Signaling Inhibitors in a Pre-clinical Model of Bowel InflammationCarolina Pellegrini, Matteo Fornai, Rocchina Colucci, et al.Chemmedchem|March 19, 2016
Design, Synthesis, and Evaluation of Acrylamide Derivatives as Direct NLRP3 Inflammasome InhibitorsMattia Cocco, Gianluca Miglio, Marta Giorgis, et al.Journal of Medicinal Chemistry|June 18, 2025
Fluorescent Isostere (Fluostere) of the Carboxylate: Design of hDHODH Fluorescent Inhibitors as Proof of ConceptStefano Sainas, Elena Martino, Claudio Garino, et al.Chemical Biology & Drug Design|May 27, 2016
Design and synthesis of N-benzoyl amino acid derivatives as DNA methylation inhibitorsDavide Garella, Sandra Atlante, Emily Borretto, et al.Cell Death & Disease|July 11, 2018
α-ketoglutarate dehydrogenase inhibition counteracts breast cancer-associated lung metastasisSandra Atlante, Alessia Visintin, Elisabetta Marini, et al.Molecules (Basel, Switzerland)|December 11, 2022
Investigation into the Use of Encorafenib to Develop Potential PROTACs Directed against BRAFV600E ProteinElisabetta Marini, Marco Marino, Giulia Gionfriddo, et al.Cancers|March 6, 2021
The Synergism between DHODH Inhibitors and Dipyridamole Leads to Metabolic Lethality in Acute Myeloid LeukemiaValentina Gaidano, Mohammad Houshmand, Nicoletta Vitale, et al.Journal of Medicinal Chemistry|April 15, 2017
Development of an Acrylate Derivative Targeting the NLRP3 Inflammasome for the Treatment of Inflammatory Bowel DiseaseMattia Cocco, Carolina Pellegrini, Helios Martínez-Banaclocha, et al.European Journal of Medicinal Chemistry|February 26, 2017
Design, synthesis, biological evaluation and X-ray structural studies of potent human dihydroorotate dehydrogenase inhibitors based on hydroxylated azole scaffoldsStefano Sainas, Agnese C Pippione, Marta Giorgis, et al.European Journal of Medicinal Chemistry|March 19, 2026
Structure-based design of new pyrazole inhibitors targeting Plasmodium falciparum dihydroorotate dehydrogenase (PfDHODH)Agnese C Pippione, Noemi Villella, Federico Fornaseri, et al.Pageof 4