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The Journal of Biological Chemistry|October 9, 2015
Competitive Inhibition of the Endoplasmic Reticulum Signal Peptidase by Non-cleavable Mutant Preprotein CargosJingqiu Cui, Wei Chen, Jinhong Sun, et al.
Health Education & Behavior : the Official Publication of the Society for Public Health Education|June 24, 2025
Provider and Parent Perspectives on Pediatric Screening for Research on Early Life AdversitySabrina R Liu, Candice Taylor Lucas, Megan Y Maxwell, et al.
The Journal of Biological Chemistry|November 9, 2017
Solution structure of an ultra-stable single-chain insulin analog connects protein dynamics to a novel mechanism of receptor bindingMichael D Glidden, Yanwu Yang, Nicholas A Smith, et al.
Frontiers in Endocrinology|March 18, 2022
Peptide Model of the Mutant Proinsulin Syndrome. I. Design and Clinical CorrelationBalamurugan Dhayalan, Michael D Glidden, Alexander N Zaykov, et al.
Protein Science : a Publication of the Protein Society|February 19, 2025
Stabilization of a protein by a single halogen-based aromatic amplifierKrystel El Hage, Balamurugan Dhayalan, Yen-Shan Chen, et al.
ACS Pharmacology & Translational Science|September 19, 2025
Ultrastable Insulin-Glucagon Fusion Protein Exploits an Endogenous Hepatic Switch to Mitigate Hypoglycemic RiskNicolas Varas, Mark A Jarosinski, Yen-Shan Chen, et al.
The Journal of Biological Chemistry|October 12, 2014
Aromatic anchor at an invariant hormone-receptor interface: function of insulin residue B24 with application to protein designVijay Pandyarajan, Brian J Smith, Nelson B Phillips, et al.
The Journal of Biological Chemistry|December 5, 2009
Contribution of residue B5 to the folding and function of insulin and IGF-I: constraints and fine-tuning in the evolution of a protein familyYouhei Sohma, Qing-xin Hua, Ming Liu, et al.
Proceedings of the National Academy of Sciences of the United States of America|July 22, 2021
Insertion of a synthetic switch into insulin provides metabolite-dependent regulation of hormone-receptor activationYen-Shan Chen, Jeremy Gleaton, Yanwu Yang, et al.
The Journal of Biological Chemistry|October 24, 2009
Crystal structure of a "nonfoldable" insulin: impaired folding efficiency despite native activityMing Liu, Zhu-Li Wan, Ying-Chi Chu, et al.
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