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Journal of Medicinal Chemistry|July 18, 2008
Substituted 6-phenyl-2-naphthols. Potent and selective nonsteroidal inhibitors of 17beta-hydroxysteroid dehydrogenase type 1 (17beta-HSD1): design, synthesis, biological evaluation, and pharmacokineticsSandrine Marchais-Oberwinkler, Patricia Kruchten, Martin Frotscher, et al.Journal of Medicinal Chemistry|March 8, 2008
Design, synthesis, and biological evaluation of (hydroxyphenyl)naphthalene and -quinoline derivatives: potent and selective nonsteroidal inhibitors of 17beta-hydroxysteroid dehydrogenase type 1 (17beta-HSD1) for the treatment of estrogen-dependent diseasesMartin Frotscher, Erika Ziegler, Sandrine Marchais-Oberwinkler, et al.The Journal of Steroid Biochemistry and Molecular Biology|January 4, 2011
17β-Hydroxysteroid dehydrogenases (17β-HSDs) as therapeutic targets: protein structures, functions, and recent progress in inhibitor developmentSandrine Marchais-Oberwinkler, Claudia Henn, Gabriele Möller, et al.Journal of Medicinal Chemistry|November 28, 2018
Highly Potent 17β-HSD2 Inhibitors with a Promising Pharmacokinetic Profile for Targeted Osteoporosis TherapyLorenz Siebenbuerger, Victor Hernandez-Olmos, Ahmed S Abdelsamie, et al.European Journal of Medicinal Chemistry|June 3, 2018
Structure-based design and profiling of novel 17β-HSD14 inhibitorsFlorian Braun, Nicole Bertoletti, Gabriele Möller, et al.Journal of Medicinal Chemistry|January 16, 2019
Targeted Endocrine Therapy: Design, Synthesis, and Proof-of-Principle of 17β-Hydroxysteroid Dehydrogenase Type 2 Inhibitors in Bone Fracture HealingAhmed S Abdelsamie, Steven Herath, Yannik Biskupek, et al.Journal of Medicinal Chemistry|July 26, 2019
Design, Synthesis, and Biological Characterization of Orally Active 17β-Hydroxysteroid Dehydrogenase Type 2 Inhibitors Targeting the Prevention of OsteoporosisAhmed S Abdelsamie, Mohamed Salah, Lorenz Siebenbürger, et al.ACS Medicinal Chemistry Letters|December 17, 2021
17β-Hydroxysteroid Dehydrogenase Type 1 Inhibition: A Potential Treatment Option for Non-Small Cell Lung CancerEmanuele M Gargano, Abdelrahman Mohamed, Ahmed S Abdelsamie, et al.Pageof 4