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Journal of Medicinal Chemistry
|
November 20, 2020
Optimization of the <i>In Vivo</i> Potency of Pyrazolopyrimidine MALT1 Protease Inhibitors by Reducing Metabolism and Increasing Potency in Whole Blood
Jean Quancard, Oliver Simic, Carole Pissot Soldermann, et al.
Nature Chemical Biology
|
January 30, 2019
An allosteric MALT1 inhibitor is a molecular corrector rescuing function in an immunodeficient patient
Jean Quancard, Theo Klein, Shan-Yu Fung, et al.
Immunology and Cell Biology
|
January 24, 2018
The T-cell fingerprint of MALT1 paracaspase revealed by selective inhibition
Maureen Bardet, Adeline Unterreiner, Claire Malinverni, et al.
Journal of Medicinal Chemistry
|
November 30, 2020
Discovery of Potent, Highly Selective, and <i>In Vivo</i> Efficacious, Allosteric MALT1 Inhibitors by Iterative Scaffold Morphing
Carole Pissot Soldermann, Oliver Simic, Martin Renatus, et al.
Molecular Cell
|
June 30, 2019
Structural Basis of BRCC36 Function in DNA Repair and Immune Regulation
Julius Rabl, Richard D Bunker, Andreas D Schenk, et al.
ACS Medicinal Chemistry Letters
|
December 20, 2023
Discovery of Ligands for TRIM58, a Novel Tissue-Selective E3 Ligase
Klemens Hoegenauer, Shaojian An, Jake Axford, et al.
Nature Communications
|
December 9, 2025
Fragment-based discovery enables direct targeting of the melanoma oncogene MITF
Deborah Castelletti, Jürgen Hinrichs, Goran Malojčić, et al.
Nature Communications
|
August 19, 2024
Author Correction: DCAF1-based PROTACs with activity against clinically validated targets overcoming intrinsic- and acquired-degrader resistance
Martin Schröder, Martin Renatus, Xiaoyou Liang, et al.
Nature Communications
|
January 4, 2024
DCAF1-based PROTACs with activity against clinically validated targets overcoming intrinsic- and acquired-degrader resistance
Martin Schröder, Martin Renatus, Xiaoyou Liang, et al.
Journal of Medicinal Chemistry
|
June 20, 2020
Structure-Based Design and Preclinical Characterization of Selective and Orally Bioavailable Factor XIa Inhibitors: Demonstrating the Power of an Integrated S1 Protease Family Approach
Edwige Lorthiois, James Roache, David Barnes-Seeman, et al.
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Showing results (21-30 of 30) with videos related to
Sort By:
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This site can display upto 30 results.
Journal of Medicinal Chemistry
|
November 20, 2020
Optimization of the <i>In Vivo</i> Potency of Pyrazolopyrimidine MALT1 Protease Inhibitors by Reducing Metabolism and Increasing Potency in Whole Blood
Jean Quancard, Oliver Simic, Carole Pissot Soldermann, et al.
Nature Chemical Biology
|
January 30, 2019
An allosteric MALT1 inhibitor is a molecular corrector rescuing function in an immunodeficient patient
Jean Quancard, Theo Klein, Shan-Yu Fung, et al.
Immunology and Cell Biology
|
January 24, 2018
The T-cell fingerprint of MALT1 paracaspase revealed by selective inhibition
Maureen Bardet, Adeline Unterreiner, Claire Malinverni, et al.
Journal of Medicinal Chemistry
|
November 30, 2020
Discovery of Potent, Highly Selective, and <i>In Vivo</i> Efficacious, Allosteric MALT1 Inhibitors by Iterative Scaffold Morphing
Carole Pissot Soldermann, Oliver Simic, Martin Renatus, et al.
Molecular Cell
|
June 30, 2019
Structural Basis of BRCC36 Function in DNA Repair and Immune Regulation
Julius Rabl, Richard D Bunker, Andreas D Schenk, et al.
ACS Medicinal Chemistry Letters
|
December 20, 2023
Discovery of Ligands for TRIM58, a Novel Tissue-Selective E3 Ligase
Klemens Hoegenauer, Shaojian An, Jake Axford, et al.
Nature Communications
|
December 9, 2025
Fragment-based discovery enables direct targeting of the melanoma oncogene MITF
Deborah Castelletti, Jürgen Hinrichs, Goran Malojčić, et al.
Nature Communications
|
August 19, 2024
Author Correction: DCAF1-based PROTACs with activity against clinically validated targets overcoming intrinsic- and acquired-degrader resistance
Martin Schröder, Martin Renatus, Xiaoyou Liang, et al.
Nature Communications
|
January 4, 2024
DCAF1-based PROTACs with activity against clinically validated targets overcoming intrinsic- and acquired-degrader resistance
Martin Schröder, Martin Renatus, Xiaoyou Liang, et al.
Journal of Medicinal Chemistry
|
June 20, 2020
Structure-Based Design and Preclinical Characterization of Selective and Orally Bioavailable Factor XIa Inhibitors: Demonstrating the Power of an Integrated S1 Protease Family Approach
Edwige Lorthiois, James Roache, David Barnes-Seeman, et al.
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of 3