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Scientific Reports|June 10, 2016
The Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Uses its C-Terminus to Regulate the A2B Adenosine ReceptorMichael J Watson, Shernita L Lee, Abigail J Marklew, et al.
JCI Insight|December 5, 2017
Nasospheroids permit measurements of CFTR-dependent fluid transportJennifer S Guimbellot, Justin M Leach, Imron G Chaudhry, et al.
American Journal of Respiratory Cell and Molecular Biology|December 17, 2016
Pharmacological Rescue of Conditionally Reprogrammed Cystic Fibrosis Bronchial Epithelial CellsMartina Gentzsch, Susan E Boyles, Chaitra Cheluvaraju, et al.
Journal of Molecular Biology|November 23, 2006
Domain interdependence in the biosynthetic assembly of CFTRLiying Cui, Luba Aleksandrov, Xiu-Bao Chang, et al.
Science Translational Medicine|August 8, 2014
Potentiator ivacaftor abrogates pharmacological correction of ΔF508 CFTR in cystic fibrosisDeborah M Cholon, Nancy L Quinney, M Leslie Fulcher, et al.
The Journal of Biological Chemistry|June 30, 2014
The N-terminal domain allosterically regulates cleavage and activation of the epithelial sodium channelPradeep Kota, Ginka Buchner, Hirak Chakraborty, et al.
The Journal of Clinical Investigation|January 20, 2007
Direct interaction with filamins modulates the stability and plasma membrane expression of CFTRWilliam R Thelin, Yun Chen, Martina Gentzsch, et al.
Journal of Molecular Biology|March 13, 2012
Allosteric modulation balances thermodynamic stability and restores function of ΔF508 CFTRAndrei A Aleksandrov, Pradeep Kota, Liying Cui, et al.
Molecular Biology of the Cell|February 3, 2021
DNAJB12 and Hsp70 triage arrested intermediates of N1303K-CFTR for endoplasmic reticulum-associated autophagyLihua He, Andrew S Kennedy, Scott Houck, et al.
American Journal of Physiology. Lung Cellular and Molecular Physiology|July 13, 2016
Restoration of R117H CFTR folding and function in human airway cells through combination treatment with VX-809 and VX-770Martina Gentzsch, Hong Y Ren, Scott A Houck, et al.
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