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Aging|December 13, 2018
Integrated multi-omics characterization reveals a distinctive metabolic signature and the role of NDUFA4L2 in promoting angiogenesis, chemoresistance, and mitochondrial dysfunction in clear cell renal cell carcinomaGiuseppe Lucarelli, Monica Rutigliano, Fabio Sallustio, et al.
Cell Death & Disease|March 26, 2021
Pharmacological targeting of the novel β-catenin chromatin-associated kinase p38α in colorectal cancer stem cell tumorspheres and organoidsMartina Lepore Signorile, Valentina Grossi, Simone Di Franco, et al.
Cell Death & Disease|February 16, 2018
Uncoupling FoxO3A mitochondrial and nuclear functions in cancer cells undergoing metabolic stress and chemotherapyValentina Celestini, Tugsan Tezil, Luciana Russo, et al.
Chembiochem : a European Journal of Chemical Biology|January 5, 2021
Discovery of an Allosteric Ligand Binding Site in SMYD3 Lysine MethyltransferaseVladimir O Talibov, Edoardo Fabini, Edward A FitzGerald, et al.
Iscience|November 18, 2020
Targeting SMYD3 to Sensitize Homologous Recombination-Proficient Tumors to PARP-Mediated Synthetic LethalityPaola Sanese, Candida Fasano, Giacomo Buscemi, et al.
Journal of Experimental & Clinical Cancer Research : CR|May 29, 2024
The novel SMYD3 inhibitor EM127 impairs DNA repair response to chemotherapy-induced DNA damage and reverses cancer chemoresistancePaola Sanese, Katia De Marco, Martina Lepore Signorile, et al.
Signal Transduction and Targeted Therapy|June 30, 2025
Tailoring a novel colorectal cancer stem cell-targeted therapy by inhibiting the SMYD3/c-MYC axisMartina Lepore Signorile, Elisabetta Di Nicola, Giovanna Forte, et al.
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