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The Journal of Biological Chemistry|September 21, 2014
Alzheimer presenilin-1 mutations dramatically reduce trimming of long amyloid β-peptides (Aβ) by γ-secretase to increase 42-to-40-residue AβMarty A Fernandez, Julia A Klutkowski, Taylor Freret, et al.
Biochemistry|September 21, 2016
Transmembrane Substrate Determinants for γ-Secretase Processing of APP CTFβMarty A Fernandez, Kelly M Biette, Georgia Dolios, et al.
The Journal of Biological Chemistry|October 13, 2017
Disruption of amyloid precursor protein ubiquitination selectively increases amyloid β (Aβ) 40 levels via presenilin 2-mediated cleavageRebecca L Williamson, Karine Laulagnier, André M Miranda, et al.
Stem Cell Reports|September 2, 2022
Loss of endosomal exchanger NHE6 leads to pathological changes in tau in human neuronsMarty A Fernandez, Fatmata Bah, Li Ma, et al.
Biochemistry|September 17, 2011
Dissociation between the processivity and total activity of γ-secretase: implications for the mechanism of Alzheimer's disease-causing presenilin mutationsOmar Quintero-Monzon, Morgan M Martin, Marty A Fernandez, et al.
Biochemistry|December 21, 2007
The contribution of naturally occurring polymorphisms in altering the biochemical and structural characteristics of HIV-1 subtype C proteaseRoxana M Coman, Arthur H Robbins, Marty A Fernandez, et al.
Acta Crystallographica. Section D, Biological Crystallography|February 25, 2010
Structure of the unbound form of HIV-1 subtype A protease: comparison with unbound forms of proteases from other HIV subtypesArthur H Robbins, Roxana M Coman, Edith Bracho-Sanchez, et al.
Brain : a Journal of Neurology|December 20, 2021
Early lysosome defects precede neurodegeneration with amyloid-β and tau aggregation in NHE6-null rat brainYouJin Lee, Morgan R Miller, Marty A Fernandez, et al.
Nature Communications|November 3, 2023
A neurodegeneration checkpoint mediated by REST protects against the onset of Alzheimer's diseaseLiviu Aron, Chenxi Qiu, Zhen Kai Ngian, et al.
Stem Cell Reports|November 21, 2017
Cell-type Dependent Alzheimer's Disease Phenotypes: Probing the Biology of Selective Neuronal VulnerabilityChristina R Muratore, Constance Zhou, Meichen Liao, et al.
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