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The Journal of Biological Chemistry|December 19, 2013
Crucial positively charged residues for ligand activation of the GPR35 receptorPingwei Zhao, Tom R Lane, Helen G L Gao, et al.
Bioorganic & Medicinal Chemistry|October 29, 2017
Novel analogs of PSNCBAM-1 as allosteric modulators of cannabinoid CB1 receptorSimone Bertini, Andrea Chicca, Francesca Gado, et al.
The Journal of Biological Chemistry|December 25, 2013
Allosteric modulation of a cannabinoid G protein-coupled receptor: binding site elucidation and relationship to G protein signalingDerek M Shore, Gemma L Baillie, Dow H Hurst, et al.
Neuropharmacology|June 30, 2006
Antinociceptive activity of chemical congeners of improgan: optimization of side chain length leads to the discovery of a new, potent, non-opioid analgesicLindsay B Hough, Iwan J P de Esch, Elwin Janssen, et al.
Cannabis and Cannabinoid Research|July 6, 2022
The NPXXY Motif Regulates β-Arrestin Recruitment by the CB1 Cannabinoid ReceptorLuciana M Leo, Rufaida Al-Zoubi, Dow P Hurst, et al.
Biochemical Pharmacology|July 12, 2002
A critical role for a tyrosine residue in the cannabinoid receptors for ligand recognitionSean D McAllister, Qing Tao, Judy Barnett-Norris, et al.
Molecular Pharmacology|September 15, 2005
(-)-7'-Isothiocyanato-11-hydroxy-1',1'-dimethylheptylhexahydrocannabinol (AM841), a high-affinity electrophilic ligand, interacts covalently with a cysteine in helix six and activates the CB1 cannabinoid receptorRobert P Picone, Atmaram D Khanolkar, Wei Xu, et al.
Proceedings of the National Academy of Sciences of the United States of America|August 27, 2014
The Two-pore channel (TPC) interactome unmasks isoform-specific roles for TPCs in endolysosomal morphology and cell pigmentationYaping Lin-Moshier, Michael V Keebler, Robert Hooper, et al.
Molecular Pharmacology|May 15, 2015
The Lysophosphatidylinositol Receptor GPR55 Modulates Pain Perception in the Periaqueductal GrayElena Deliu, Margaret Sperow, Linda Console-Bram, et al.
The Journal of Biological Chemistry|June 28, 2007
Helix 8 Leu in the CB1 cannabinoid receptor contributes to selective signal transduction mechanismsSharon Anavi-Goffer, Daniel Fleischer, Dow P Hurst, et al.
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