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Investigational New Drugs
|
February 21, 2018
Involvement of NF-κB in mediating the anti-tumour effects of combretastatins in T cells
Jade K Pollock, Lisa M Greene, Seema M Nathwani, et al.
Journal of Chemical Information and Modeling
|
August 3, 2012
Study of E/Z isomerization in a series of novel non-ligand binding pocket androgen receptor antagonists
Fernando Blanco, Billy Egan, Laura Caboni, et al.
Bioorganic Chemistry
|
October 7, 2023
Synthesis by diastereomeric resolution, biochemical evaluation and molecular modelling of chiral 3-hydroxyl b-lactam microtubule-targeting agents for the treatment of triple negative breast and chemoresistant colorectal cancers
Eavan C McLoughlin, Brendan Twamley, John E O'Brien, et al.
Medicinal Chemistry (Shariqah (United Arab Emirates))
|
October 4, 2017
Synthesis, Antiproliferative and Pro-Apoptotic Effects of Nitrostyrenes and Related Compounds in Burkitt's Lymphoma
Andrew J Byrne, Sandra A Bright, Darren Fayne, et al.
Journal of Medicinal Chemistry
|
October 29, 2004
Benzoxepin-derived estrogen receptor modulators: a novel molecular scaffold for the estrogen receptor
David G Lloyd, Rosario B Hughes, Daniela M Zisterer, et al.
Molecules (Basel, Switzerland)
|
September 1, 2017
Novel Selective Estrogen Receptor Ligand Conjugates Incorporating Endoxifen-Combretastatin and Cyclofenil-Combretastatin Hybrid Scaffolds: Synthesis and Biochemical Evaluation
Patrick M Kelly, Niall O Keely, Sandra A Bright, et al.
Pharmaceuticals (Basel, Switzerland)
|
March 29, 2023
30th Annual GP<sub>2</sub>A Medicinal Chemistry Conference
Niamh M O'Boyle, Jean-Jacques Helesbeux, Mary J Meegan, et al.
Oncology Reports
|
December 13, 2012
Novel cis-restricted β-lactam combretastatin A-4 analogues display anti-vascular and anti-metastatic properties in vitro
Seema-Maria Nathwani, Linda Hughes, Lisa M Greene, et al.
Bioorganic & Medicinal Chemistry
|
March 15, 2011
Synthesis, evaluation and structural studies of antiproliferative tubulin-targeting azetidin-2-ones
Niamh M O'Boyle, Lisa M Greene, Orla Bergin, et al.
Bioorganic & Medicinal Chemistry
|
September 17, 2011
Lead identification of β-lactam and related imine inhibitors of the molecular chaperone heat shock protein 90
Niamh M O'Boyle, Andrew J S Knox, Trevor T Price, et al.
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Search research articles
Search
Showing results (31-40 of 71) with videos related to
Sort By:
Page
of 8
Investigational New Drugs
|
February 21, 2018
Involvement of NF-κB in mediating the anti-tumour effects of combretastatins in T cells
Jade K Pollock, Lisa M Greene, Seema M Nathwani, et al.
Journal of Chemical Information and Modeling
|
August 3, 2012
Study of E/Z isomerization in a series of novel non-ligand binding pocket androgen receptor antagonists
Fernando Blanco, Billy Egan, Laura Caboni, et al.
Bioorganic Chemistry
|
October 7, 2023
Synthesis by diastereomeric resolution, biochemical evaluation and molecular modelling of chiral 3-hydroxyl b-lactam microtubule-targeting agents for the treatment of triple negative breast and chemoresistant colorectal cancers
Eavan C McLoughlin, Brendan Twamley, John E O'Brien, et al.
Medicinal Chemistry (Shariqah (United Arab Emirates))
|
October 4, 2017
Synthesis, Antiproliferative and Pro-Apoptotic Effects of Nitrostyrenes and Related Compounds in Burkitt's Lymphoma
Andrew J Byrne, Sandra A Bright, Darren Fayne, et al.
Journal of Medicinal Chemistry
|
October 29, 2004
Benzoxepin-derived estrogen receptor modulators: a novel molecular scaffold for the estrogen receptor
David G Lloyd, Rosario B Hughes, Daniela M Zisterer, et al.
Molecules (Basel, Switzerland)
|
September 1, 2017
Novel Selective Estrogen Receptor Ligand Conjugates Incorporating Endoxifen-Combretastatin and Cyclofenil-Combretastatin Hybrid Scaffolds: Synthesis and Biochemical Evaluation
Patrick M Kelly, Niall O Keely, Sandra A Bright, et al.
Pharmaceuticals (Basel, Switzerland)
|
March 29, 2023
30th Annual GP<sub>2</sub>A Medicinal Chemistry Conference
Niamh M O'Boyle, Jean-Jacques Helesbeux, Mary J Meegan, et al.
Oncology Reports
|
December 13, 2012
Novel cis-restricted β-lactam combretastatin A-4 analogues display anti-vascular and anti-metastatic properties in vitro
Seema-Maria Nathwani, Linda Hughes, Lisa M Greene, et al.
Bioorganic & Medicinal Chemistry
|
March 15, 2011
Synthesis, evaluation and structural studies of antiproliferative tubulin-targeting azetidin-2-ones
Niamh M O'Boyle, Lisa M Greene, Orla Bergin, et al.
Bioorganic & Medicinal Chemistry
|
September 17, 2011
Lead identification of β-lactam and related imine inhibitors of the molecular chaperone heat shock protein 90
Niamh M O'Boyle, Andrew J S Knox, Trevor T Price, et al.
Page
of 8