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Current Diabetes Reports|July 27, 2013
Antigen-based vaccination and prevention of type 1 diabetesLeonard C Harrison, John M Wentworth, Yuxia Zhang, et al.
Science Advances|July 9, 2025
NLRP3 inflammasome-driven hemophagocytic lymphohistiocytosis occurs independent of IL-1β and IL-18 and is targetable by BET inhibitorsFarzaneh Shojaee, Esmaeel Azadian, Min Xian Wong, et al.
Nature Communications|May 12, 2021
The ubiquitylation of IL-1β limits its cleavage by caspase-1 and targets it for proteasomal degradationSwarna L Vijayaraj, Rebecca Feltham, Maryam Rashidi, et al.
Nature Communications|February 19, 2015
RIPK3 promotes cell death and NLRP3 inflammasome activation in the absence of MLKLKate E Lawlor, Nufail Khan, Alison Mildenhall, et al.
Iscience|July 8, 2022
Ubiquitylation of RIPK3 beyond-the-RHIM can limit RIPK3 activity and cell deathDaniel Frank, Sarah E Garnish, Jarrod J Sandow, et al.
The EMBO Journal|January 17, 2023
Caspase-8-driven apoptotic and pyroptotic crosstalk causes cell death and IL-1β release in X-linked inhibitor of apoptosis (XIAP) deficiencySebastian A Hughes, Meng Lin, Ashley Weir, et al.
Life Science Alliance|November 12, 2024
Divergent roles of RIPK3 and MLKL in high-fat diet-induced obesity and MAFLD in miceHazel Tye, Stephanie A Conos, Tirta M Djajawi, et al.
Immunity|February 9, 2022
Interferon-γ primes macrophages for pathogen ligand-induced killing via a caspase-8 and mitochondrial cell death pathwayDaniel S Simpson, Jiyi Pang, Ashley Weir, et al.
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