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Chemical Science
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August 11, 2023
Fragment expansion with NUDELs - poised DNA-encoded libraries
Catherine L A Salvini, Benoit Darlot, Jack Davison, et al.
Journal of Medicinal Chemistry
|
August 9, 2022
Build-Couple-Transform: A Paradigm for Lead-like Library Synthesis with Scaffold Diversity
Mélanie Uguen, Gemma Davison, Lukas J Sprenger, et al.
Communications Chemistry
|
April 9, 2025
Factors affecting irreversible inhibition of EGFR and influence of chirality on covalent binding
Pasquale A Morese, Ayaz Ahmad, Mathew P Martin, et al.
Journal of Medicinal Chemistry
|
January 26, 2012
Fragment-based and structure-guided discovery and optimization of Rho kinase inhibitors
Rongshi Li, Mathew P Martin, Yan Liu, et al.
Journal of Medicinal Chemistry
|
March 13, 2019
FragLites-Minimal, Halogenated Fragments Displaying Pharmacophore Doublets. An Efficient Approach to Druggability Assessment and Hit Generation
Daniel J Wood, J Daniel Lopez-Fernandez, Leanne E Knight, et al.
Organic & Biomolecular Chemistry
|
February 23, 2018
Identification of a novel ligand for the ATAD2 bromodomain with selectivity over BRD4 through a fragment growing approach
Duncan C Miller, Mathew P Martin, Santosh Adhikari, et al.
Journal of Medicinal Chemistry
|
April 23, 2013
Development of highly potent and selective diaminothiazole inhibitors of cyclin-dependent kinases
Ernst Schonbrunn, Stephane Betzi, Riazul Alam, et al.
Journal of Medicinal Chemistry
|
September 12, 2022
A Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Assay Identifies Nilotinib as an Inhibitor of Inflammation in Acute Myeloid Leukemia
José Luis Marín-Rubio, Rachel E Peltier-Heap, Maria Emilia Dueñas, et al.
Journal of Medicinal Chemistry
|
August 30, 2023
Targeting Cytotoxic Agents through EGFR-Mediated Covalent Binding and Release
Pasquale A Morese, Nahoum Anthony, Michael Bodnarchuk, et al.
Journal of Medicinal Chemistry
|
November 11, 2022
Mapping Ligand Interactions of Bromodomains BRD4 and ATAD2 with FragLites and PepLites─Halogenated Probes of Druglike and Peptide-like Molecular Interactions
Gemma Davison, Mathew P Martin, Shannon Turberville, et al.
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of 4
Search research articles
Search
Showing results (21-30 of 38) with videos related to
Sort By:
Page
of 4
Chemical Science
|
August 11, 2023
Fragment expansion with NUDELs - poised DNA-encoded libraries
Catherine L A Salvini, Benoit Darlot, Jack Davison, et al.
Journal of Medicinal Chemistry
|
August 9, 2022
Build-Couple-Transform: A Paradigm for Lead-like Library Synthesis with Scaffold Diversity
Mélanie Uguen, Gemma Davison, Lukas J Sprenger, et al.
Communications Chemistry
|
April 9, 2025
Factors affecting irreversible inhibition of EGFR and influence of chirality on covalent binding
Pasquale A Morese, Ayaz Ahmad, Mathew P Martin, et al.
Journal of Medicinal Chemistry
|
January 26, 2012
Fragment-based and structure-guided discovery and optimization of Rho kinase inhibitors
Rongshi Li, Mathew P Martin, Yan Liu, et al.
Journal of Medicinal Chemistry
|
March 13, 2019
FragLites-Minimal, Halogenated Fragments Displaying Pharmacophore Doublets. An Efficient Approach to Druggability Assessment and Hit Generation
Daniel J Wood, J Daniel Lopez-Fernandez, Leanne E Knight, et al.
Organic & Biomolecular Chemistry
|
February 23, 2018
Identification of a novel ligand for the ATAD2 bromodomain with selectivity over BRD4 through a fragment growing approach
Duncan C Miller, Mathew P Martin, Santosh Adhikari, et al.
Journal of Medicinal Chemistry
|
April 23, 2013
Development of highly potent and selective diaminothiazole inhibitors of cyclin-dependent kinases
Ernst Schonbrunn, Stephane Betzi, Riazul Alam, et al.
Journal of Medicinal Chemistry
|
September 12, 2022
A Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Assay Identifies Nilotinib as an Inhibitor of Inflammation in Acute Myeloid Leukemia
José Luis Marín-Rubio, Rachel E Peltier-Heap, Maria Emilia Dueñas, et al.
Journal of Medicinal Chemistry
|
August 30, 2023
Targeting Cytotoxic Agents through EGFR-Mediated Covalent Binding and Release
Pasquale A Morese, Nahoum Anthony, Michael Bodnarchuk, et al.
Journal of Medicinal Chemistry
|
November 11, 2022
Mapping Ligand Interactions of Bromodomains BRD4 and ATAD2 with FragLites and PepLites─Halogenated Probes of Druglike and Peptide-like Molecular Interactions
Gemma Davison, Mathew P Martin, Shannon Turberville, et al.
Page
of 4