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Pharmacogenetics and Genomics|December 5, 2017
Angiotensin-converting enzyme activity in Cavalier King Charles Spaniels with an ACE gene polymorphism and myxomatous mitral valve diseaseKathryn M Meurs, Lisbeth H Olsen, Maria J Reimann, et al.
The Journal of Biological Chemistry|January 12, 2010
SRT1720, SRT2183, SRT1460, and resveratrol are not direct activators of SIRT1Michelle Pacholec, John E Bleasdale, Boris Chrunyk, et al.
Plos One|March 23, 2011
Beaked whales respond to simulated and actual navy sonarPeter L Tyack, Walter M X Zimmer, David Moretti, et al.
The Journal of Biological Chemistry|January 30, 2023
Structural studies identify angiotensin II receptor blocker-like compounds as branched-chain ketoacid dehydrogenase kinase inhibitorsShenping Liu, Bethany L Kormos, John D Knafels, et al.
The Journal of Pharmacology and Experimental Therapeutics|February 21, 2015
PF-1355, a mechanism-based myeloperoxidase inhibitor, prevents immune complex vasculitis and anti-glomerular basement membrane glomerulonephritisWei Zheng, Roscoe Warner, Roger Ruggeri, et al.
Journal of Medicinal Chemistry|July 24, 2018
Acyl Glucuronide Metabolites of 6-Chloro-5-[4-(1-hydroxycyclobutyl)phenyl]-1 H-indole-3-carboxylic Acid (PF-06409577) and Related Indole-3-carboxylic Acid Derivatives are Direct Activators of Adenosine Monophosphate-Activated Protein Kinase (AMPK)Tim F Ryder, Matthew F Calabrese, Gregory S Walker, et al.
The Journal of Biological Chemistry|November 15, 2025
Discovery of small molecule modulators of the thin filament that alter the contractile profile in a hypertrophic cardiomyopathy engineered tissue modelRuth F Sommese, Samuel M Levi, Janice Brown, et al.
Journal of Medicinal Chemistry|April 10, 2018
Discovery of a Novel Small-Molecule Modulator of C-X-C Chemokine Receptor Type 7 as a Treatment for Cardiac FibrosisElnaz Menhaji-Klotz, Kevin D Hesp, Allyn T Londregan, et al.
Ebiomedicine|April 21, 2018
Activation of Liver AMPK with PF-06409577 Corrects NAFLD and Lowers Cholesterol in Rodent and Primate Preclinical ModelsRyan M Esquejo, Christopher T Salatto, Jake Delmore, et al.
The Journal of Pharmacology and Experimental Therapeutics|March 15, 2017
Selective Activation of AMPK <i>β</i>1-Containing Isoforms Improves Kidney Function in a Rat Model of Diabetic NephropathyChristopher T Salatto, Russell A Miller, Kimberly O Cameron, et al.
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