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Biochimica Et Biophysica Acta. Molecular Basis of Disease|December 7, 2023
The hypermorphic PLCγ2 S707Y variant dysregulates microglial cell function - Insight into PLCγ2 activation in brain health and disease, and opportunities for therapeutic modulationDaniel Bull, Julie C Matte, Carmen M Navarron, et al.Bioorganic & Medicinal Chemistry|March 24, 2009
The identification of novel PLC-gamma inhibitors using virtual high throughput screeningJóhannes Reynisson, William Court, Ciaran O'Neill, et al.Advances in Biological Regulation|October 21, 2015
Time-resolved FRET reports FGFR1 dimerization and formation of a complex with its effector PLCγ1Louis Perdios, Tom D Bunney, Sean C Warren, et al.Proceedings of the National Academy of Sciences of the United States of America|March 5, 2014
Tumor suppressor role of phospholipase C epsilon in Ras-triggered cancersMarta Martins, Afshan McCarthy, Rhona Baxendale, et al.Scientific Reports|January 23, 2025
Cell-free expression and SMA copolymer encapsulation of a functional receptor tyrosine kinase disease variant, FGFR3-TACC3Alexander J D Snow, Tharushi Wijesiriwardena, Benjamin J Lane, et al.BMB Reports|July 3, 2008
Multiple roles of phosphoinositide-specific phospholipase C isozymesPann-Ghill Suh, Jae-Il Park, Lucia Manzoli, et al.Scientific Reports|June 25, 2016
Screening for protein-protein interactions using Förster resonance energy transfer (FRET) and fluorescence lifetime imaging microscopy (FLIM)Anca Margineanu, Jia Jia Chan, Douglas J Kelly, et al.Plos One|August 14, 2013
Rapid global fitting of large fluorescence lifetime imaging microscopy datasetsSean C Warren, Anca Margineanu, Dominic Alibhai, et al.Structure (London, England : 1993)|October 16, 2012
Structural and functional integration of the PLCγ interaction domains critical for regulatory mechanisms and signaling deregulationTom D Bunney, Diego Esposito, Corine Mas-Droux, et al.Journal of Cell Science|September 21, 2012
Activity of PLCε contributes to chemotaxis of fibroblasts towards PDGFMarta Martins, Sean Warren, Christopher Kimberley, et al.Pageof 7