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Journal of Medicinal Chemistry
|
March 8, 2021
Generating Selective Leads for Mer Kinase Inhibitors-Example of a Comprehensive Lead-Generation Strategy
J Willem M Nissink, Sana Bazzaz, Carolyn Blackett, et al.
Journal of Medicinal Chemistry
|
April 12, 2021
Bispecific Estrogen Receptor α Degraders Incorporating Novel Binders Identified Using DNA-Encoded Chemical Library Screening
Jeremy S Disch, Jennifer M Duffy, Esther C Y Lee, et al.
Journal of Medicinal Chemistry
|
October 25, 2024
Rational Design of Macrocyclic Noncovalent Inhibitors of SARS-CoV-2 M<sup>pro</sup> from a DNA-Encoded Chemical Library Screening Hit That Demonstrate Potent Inhibition against Pan-Coronavirus Homologues and Nirmatrelvir-Resistant Variants
Xu Wang, Dimitar Gotchev, Kristi Yi Fan, et al.
Journal of Medicinal Chemistry
|
August 16, 2012
Discovery of highly potent and selective small molecule ADAMTS-5 inhibitors that inhibit human cartilage degradation via encoded library technology (ELT)
Hongfeng Deng, Heather O'Keefe, Christopher P Davie, et al.
Journal of Medicinal Chemistry
|
February 2, 2024
Development of Potent Mcl-1 Inhibitors: Structural Investigations on Macrocycles Originating from a DNA-Encoded Chemical Library Screen
Koen F W Hekking, Sergio Maroto, Kees van Kekem, et al.
ACS Chemical Biology
|
October 19, 2017
Isoform-Selective ATAD2 Chemical Probe with Novel Chemical Structure and Unusual Mode of Action
Amaury E Fernández-Montalván, Markus Berger, Benno Kuropka, et al.
Journal of Medicinal Chemistry
|
January 24, 2014
Encoded library technology as a source of hits for the discovery and lead optimization of a potent and selective class of bactericidal direct inhibitors of Mycobacterium tuberculosis InhA
Lourdes Encinas, Heather O'Keefe, Margarete Neu, et al.
ACS Medicinal Chemistry Letters
|
August 20, 2015
Discovery, SAR, and X-ray Binding Mode Study of BCATm Inhibitors from a Novel DNA-Encoded Library
Hongfeng Deng, Jingye Zhou, Flora S Sundersingh, et al.
ACS Medicinal Chemistry Letters
|
November 19, 2025
A Novel Small Molecule Allosteric Inhibitor of IL-17A from a DNA-Encoded Library
Marcos E Milla, Jonathan M Blevitt, Steven D Goldberg, et al.
ACS Medicinal Chemistry Letters
|
November 21, 2017
Correction to "Structure Based Design of Non-Natural Peptidic Macrocyclic Mcl-1 Inhibitors"
Jeffrey W Johannes, Stephanie Bates, Carl Beigie, et al.
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Search research articles
Search
Showing results (41-50 of 54) with videos related to
Sort By:
Page
of 6
Journal of Medicinal Chemistry
|
March 8, 2021
Generating Selective Leads for Mer Kinase Inhibitors-Example of a Comprehensive Lead-Generation Strategy
J Willem M Nissink, Sana Bazzaz, Carolyn Blackett, et al.
Journal of Medicinal Chemistry
|
April 12, 2021
Bispecific Estrogen Receptor α Degraders Incorporating Novel Binders Identified Using DNA-Encoded Chemical Library Screening
Jeremy S Disch, Jennifer M Duffy, Esther C Y Lee, et al.
Journal of Medicinal Chemistry
|
October 25, 2024
Rational Design of Macrocyclic Noncovalent Inhibitors of SARS-CoV-2 M<sup>pro</sup> from a DNA-Encoded Chemical Library Screening Hit That Demonstrate Potent Inhibition against Pan-Coronavirus Homologues and Nirmatrelvir-Resistant Variants
Xu Wang, Dimitar Gotchev, Kristi Yi Fan, et al.
Journal of Medicinal Chemistry
|
August 16, 2012
Discovery of highly potent and selective small molecule ADAMTS-5 inhibitors that inhibit human cartilage degradation via encoded library technology (ELT)
Hongfeng Deng, Heather O'Keefe, Christopher P Davie, et al.
Journal of Medicinal Chemistry
|
February 2, 2024
Development of Potent Mcl-1 Inhibitors: Structural Investigations on Macrocycles Originating from a DNA-Encoded Chemical Library Screen
Koen F W Hekking, Sergio Maroto, Kees van Kekem, et al.
ACS Chemical Biology
|
October 19, 2017
Isoform-Selective ATAD2 Chemical Probe with Novel Chemical Structure and Unusual Mode of Action
Amaury E Fernández-Montalván, Markus Berger, Benno Kuropka, et al.
Journal of Medicinal Chemistry
|
January 24, 2014
Encoded library technology as a source of hits for the discovery and lead optimization of a potent and selective class of bactericidal direct inhibitors of Mycobacterium tuberculosis InhA
Lourdes Encinas, Heather O'Keefe, Margarete Neu, et al.
ACS Medicinal Chemistry Letters
|
August 20, 2015
Discovery, SAR, and X-ray Binding Mode Study of BCATm Inhibitors from a Novel DNA-Encoded Library
Hongfeng Deng, Jingye Zhou, Flora S Sundersingh, et al.
ACS Medicinal Chemistry Letters
|
November 19, 2025
A Novel Small Molecule Allosteric Inhibitor of IL-17A from a DNA-Encoded Library
Marcos E Milla, Jonathan M Blevitt, Steven D Goldberg, et al.
ACS Medicinal Chemistry Letters
|
November 21, 2017
Correction to "Structure Based Design of Non-Natural Peptidic Macrocyclic Mcl-1 Inhibitors"
Jeffrey W Johannes, Stephanie Bates, Carl Beigie, et al.
Page
of 6