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The Journal of Antimicrobial Chemotherapy|May 10, 2017
Development of a murine vertical transmission model for Toxoplasma gondii oocyst infection and studies on the efficacy of bumped kinase inhibitor (BKI)-1294 and the naphthoquinone buparvaquone against congenital toxoplasmosisJoachim Müller, Adriana Aguado-Martínez, Luis-Miguel Ortega-Mora, et al.
ACS Infectious Diseases|February 10, 2021
Pyrrolopyrimidine Bumped Kinase Inhibitors for the Treatment of CryptosporidiosisMatthew A Hulverson, Ryan Choi, Rama S R Vidadala, et al.
The Journal of Infectious Diseases|June 11, 2019
P-Glycoprotein-Mediated Efflux Reduces the In Vivo Efficacy of a Therapeutic Targeting the Gastrointestinal Parasite CryptosporidiumSamuel L M Arnold, Ryan Choi, Matthew A Hulverson, et al.
Journal of Medicinal Chemistry|March 5, 2019
Development of 5-Aminopyrazole-4-carboxamide-based Bumped-Kinase Inhibitors for Cryptosporidiosis TherapyWenlin Huang, Matthew A Hulverson, Ryan Choi, et al.
Antimicrobial Agents and Chemotherapy|March 21, 2018
Toxoplasma Calcium-Dependent Protein Kinase 1 Inhibitors: Probing Activity and Resistance Using Cellular Thermal Shift AssaysSuzanne Scheele, Jennifer A Geiger, Amy E DeRocher, et al.
ACS Infectious Diseases|September 15, 2016
5-Fluoroimidazo[4,5-b]pyridine Is a Privileged Fragment That Conveys Bioavailability to Potent Trypanosomal Methionyl-tRNA Synthetase InhibitorsZhongsheng Zhang, Cho Yeow Koh, Ranae M Ranade, et al.
Antimicrobial Agents and Chemotherapy|April 18, 2018
Therapeutic Efficacy of Bumped Kinase Inhibitor 1369 in a Pig Model of Acute Diarrhea Caused by Cryptosporidium hominisSangun Lee, Melanie Ginese, Gillian Beamer, et al.
The Journal of Infectious Diseases|May 4, 2026
Structure-guided design of calcium-dependent protein kinase 1 (CDPK1) inhibitors for cryptosporidiosisWissarut Wijitrmektong, Ryan Choi, Matthew A Hulverson, et al.
Antimicrobial Agents and Chemotherapy|May 24, 2017
5-Aminopyrazole-4-Carboxamide-Based Compounds Prevent the Growth of Cryptosporidium parvumWenlin Huang, Ryan Choi, Matthew A Hulverson, et al.
International Journal for Parasitology. Drugs and Drug Resistance|May 24, 2021
In vitro activity, safety and in vivo efficacy of the novel bumped kinase inhibitor BKI-1748 in non-pregnant and pregnant mice experimentally infected with Neospora caninum tachyzoites and Toxoplasma gondii oocystsDennis Imhof, Nicoleta Anghel, Pablo Winzer, et al.
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