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American Journal of Veterinary Research|October 14, 2025
Pharmacokinetic analysis of bumped-kinase inhibitors in horses demonstrates their potential utility for prevention and treatment of equine protozoal myeloencephalitisIzabela de Assis Rocha, Jenna L McPeek, Matthew A Hulverson, et al.Antimicrobial Agents and Chemotherapy|May 8, 2019
Treatment with Bumped Kinase Inhibitor 1294 Is Safe and Leads to Significant Protection against Abortion and Vertical Transmission in Sheep Experimentally Infected with Toxoplasma gondii during PregnancyRoberto Sánchez-Sánchez, Ignacio Ferre, Michela Re, et al.The Journal of Infectious Diseases|April 20, 2026
Effective Treatment using Bumped Kinase Inhibitor 1708 in a Calf Clinical Model of CryptosporidiosisDeborah A Schaefer, Dana P Betzer, Kevin Ackman, et al.International Journal for Parasitology. Drugs and Drug Resistance|April 9, 2019
Bumped kinase inhibitor 1369 is effective against Cystoisospora suis in vivo and in vitroAruna Shrestha, Kayode K Ojo, Florian Koston, et al.International Journal for Parasitology. Drugs and Drug Resistance|October 16, 2021
A short-term treatment with BKI-1294 does not protect foetuses from sheep experimentally infected with Neospora caninum tachyzoites during pregnancyRoberto Sánchez-Sánchez, Ignacio Ferre, Michela Re, et al.The Journal of Infectious Diseases|May 26, 2017
Necessity of Bumped Kinase Inhibitor Gastrointestinal Exposure in Treating Cryptosporidium InfectionSamuel L M Arnold, Ryan Choi, Matthew A Hulverson, et al.Antimicrobial Agents and Chemotherapy|February 13, 2019
Optimization of Methionyl tRNA-Synthetase Inhibitors for Treatment of Cryptosporidium InfectionFrederick S Buckner, Ranae M Ranade, J Robert Gillespie, et al.The Journal of Infectious Diseases|November 14, 2018
Pharmacokinetics and In Vivo Efficacy of Pyrazolopyrimidine, Pyrrolopyrimidine, and 5-Aminopyrazole-4-Carboxamide Bumped Kinase Inhibitors against ToxoplasmosisMatthew A Hulverson, Igor Bruzual, Erin V McConnell, et al.The Journal of Infectious Diseases|December 8, 2016
Novel Bumped Kinase Inhibitors Are Safe and Effective Therapeutics in the Calf Clinical Model for CryptosporidiosisDeborah A Schaefer, Dana P Betzer, Kylie D Smith, et al.ACS Infectious Diseases|March 19, 2021
Repurposing Infectious Disease Hits as Anti-Cryptosporidium LeadsMatthew A Hulverson, Ryan Choi, Molly C McCloskey, et al.Pageof 7