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Data in Brief|October 21, 2016
Data on the purification and crystallization of the loss-of-function von Willebrand disease variant (p.Gly1324Ser) of the von Willebrand factor A1 domainJames C Campbell, Alexander Tischer, Venkata Machha, et al.
Biophysical Chemistry|August 12, 2015
Thermodynamic and fibril formation studies of full length immunoglobulin light chain AL-09 and its germline protein using scan rate dependent thermal unfoldingLuis M Blancas-Mejía, Timothy J Horn, Marta Marin-Argany, et al.
Journal of Molecular Biology|October 26, 2013
Kinetic control in protein folding for light chain amyloidosis and the differential effects of somatic mutationsLuis M Blancas-Mejía, Alexander Tischer, James R Thompson, et al.
Plos Pathogens|February 3, 2021
MeV-Stealth: A CD46-specific oncolytic measles virus resistant to neutralization by measles-immune human serumMiguel Ángel Muñoz-Alía, Rebecca A Nace, Alexander Tischer, et al.
The Journal of Biological Chemistry|December 18, 2015
Mutational Constraints on Local Unfolding Inhibit the Rheological Adaptation of von Willebrand FactorAlexander Tischer, James C Campbell, Venkata R Machha, et al.
Biochimica Et Biophysica Acta. Proteins and Proteomics|January 3, 2024
Biophysical characterization of human-cell-expressed, full-length κI O18/O8, AL-09, λ6a, and Wil immunoglobulin light chainsPinaki Misra, Alexander Tischer, Lindsey Lampe, et al.
Blood Advances|October 7, 2021
A p.Arg127Gln variant in GPIbα LRR5 allosterically enhances affinity for VWF: a novel form of platelet-type VWDLoredana Bury, Emanuela Falcinelli, Haripriya Kuchi Bhotla, et al.
Journal of Molecular Biology|May 24, 2017
Enhanced Local Disorder in a Clinically Elusive von Willebrand Factor Provokes High-Affinity Platelet ClumpingAlexander Tischer, Venkata R Machha, Juan P Frontroth, et al.
NAR Molecular Medicine|December 25, 2024
Conformation-specific RNA aptamers for phenotypic distinction between normal von Willebrand factor and type 2B von Willebrand diseaseVenkata R Machha, Alexander Tischer, Laurie Moon-Tasson, et al.
ACS Omega|January 19, 2026
Biophysical Characterization and Structural Insights Into the Complex between the Extracytoplasmic Function Sigma Factor, PupI, with the Antisigma Domain of the Sigma Regulator, PupR, from Pseudomonas capeferrumTajnin Sultana, Robin N Kutsi, Alexander Tischer, et al.
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