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SLAS Discovery : Advancing Life Sciences R & D
|
August 11, 2025
Identification of novel inflammasome inhibitors via cellular NLRP3 target engagement assays
Francisco Castillo, Thomas A Mackenzie, Elisabeth Domingo, et al.
Cell Chemical Biology
|
August 29, 2023
Protomer selectivity of type II RAF inhibitors within the RAS/RAF complex
James D Vasta, Ani Michaud, Chad A Zimprich, et al.
Nature Methods
|
June 2, 2015
Application of BRET to monitor ligand binding to GPCRs
Leigh A Stoddart, Elizabeth K M Johnstone, Amanda J Wheal, et al.
Analytical Biochemistry
|
August 18, 2015
A luminescent assay for real-time measurements of receptor endocytosis in living cells
Matthew B Robers, Brock F Binkowski, Mei Cong, et al.
ACS Chemical Biology
|
July 12, 2015
Deciphering the Cellular Targets of Bioactive Compounds Using a Chloroalkane Capture Tag
Rachel Friedman Ohana, Thomas A Kirkland, Carolyn C Woodroofe, et al.
Proceedings of the National Academy of Sciences of the United States of America
|
November 9, 2021
Mutation in Abl kinase with altered drug-binding kinetics indicates a novel mechanism of imatinib resistance
Agatha Lyczek, Benedict-Tilman Berger, Aziz M Rangwala, et al.
Journal of Medicinal Chemistry
|
August 16, 2019
Discovery of a New Isoxazole-3-hydroxamate-Based Histone Deacetylase 6 Inhibitor SS-208 with Antitumor Activity in Syngeneic Melanoma Mouse Models
Sida Shen, Melissa Hadley, Kseniya Ustinova, et al.
Nature Chemical Biology
|
January 6, 2026
Advances in BRET probes for intracellular target engagement studies
Jacob L Capener, Martin P Schwalm, James D Vasta, et al.
Journal of the American Chemical Society
|
October 27, 2018
Binding Kinetics Survey of the Drugged Kinome
Victoria Georgi, Felix Schiele, Benedict-Tilman Berger, et al.
ACS Medicinal Chemistry Letters
|
June 26, 2018
Homogeneous Assay for Target Engagement Utilizing Bioluminescent Thermal Shift
Melanie L Dart, Thomas Machleidt, Emily Jost, et al.
Page
of 7
Search research articles
Search
Showing results (31-40 of 67) with videos related to
Sort By:
Page
of 7
SLAS Discovery : Advancing Life Sciences R & D
|
August 11, 2025
Identification of novel inflammasome inhibitors via cellular NLRP3 target engagement assays
Francisco Castillo, Thomas A Mackenzie, Elisabeth Domingo, et al.
Cell Chemical Biology
|
August 29, 2023
Protomer selectivity of type II RAF inhibitors within the RAS/RAF complex
James D Vasta, Ani Michaud, Chad A Zimprich, et al.
Nature Methods
|
June 2, 2015
Application of BRET to monitor ligand binding to GPCRs
Leigh A Stoddart, Elizabeth K M Johnstone, Amanda J Wheal, et al.
Analytical Biochemistry
|
August 18, 2015
A luminescent assay for real-time measurements of receptor endocytosis in living cells
Matthew B Robers, Brock F Binkowski, Mei Cong, et al.
ACS Chemical Biology
|
July 12, 2015
Deciphering the Cellular Targets of Bioactive Compounds Using a Chloroalkane Capture Tag
Rachel Friedman Ohana, Thomas A Kirkland, Carolyn C Woodroofe, et al.
Proceedings of the National Academy of Sciences of the United States of America
|
November 9, 2021
Mutation in Abl kinase with altered drug-binding kinetics indicates a novel mechanism of imatinib resistance
Agatha Lyczek, Benedict-Tilman Berger, Aziz M Rangwala, et al.
Journal of Medicinal Chemistry
|
August 16, 2019
Discovery of a New Isoxazole-3-hydroxamate-Based Histone Deacetylase 6 Inhibitor SS-208 with Antitumor Activity in Syngeneic Melanoma Mouse Models
Sida Shen, Melissa Hadley, Kseniya Ustinova, et al.
Nature Chemical Biology
|
January 6, 2026
Advances in BRET probes for intracellular target engagement studies
Jacob L Capener, Martin P Schwalm, James D Vasta, et al.
Journal of the American Chemical Society
|
October 27, 2018
Binding Kinetics Survey of the Drugged Kinome
Victoria Georgi, Felix Schiele, Benedict-Tilman Berger, et al.
ACS Medicinal Chemistry Letters
|
June 26, 2018
Homogeneous Assay for Target Engagement Utilizing Bioluminescent Thermal Shift
Melanie L Dart, Thomas Machleidt, Emily Jost, et al.
Page
of 7