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Matthew D Disney

Showing results (201-210 of 213) with videos related to

Pageof 22
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Molecular Neurodegeneration|February 16, 2019
Aberrant deposition of stress granule-resident proteins linked to C9orf72-associated TDP-43 proteinopathyJeannie Chew, Casey Cook, Tania F Gendron, et al.
Nature Communications|June 29, 2013
Induction and reversal of myotonic dystrophy type 1 pre-mRNA splicing defects by small moleculesJessica L Childs-Disney, Ewa Stepniak-Konieczna, Tuan Tran, et al.
Journal of the American Chemical Society|May 5, 2020
Design, Optimization, and Study of Small Molecules That Target Tau Pre-mRNA and Affect SplicingJonathan L Chen, Peiyuan Zhang, Masahito Abe, et al.
Journal of the American Chemical Society|October 6, 2025
Covalent Probes Reveal Small-Molecule Binding Pockets in Structured RNA and Enable Bioactive Compound DesignSandra Kovachka, Jielei Wang, Amirhossein Taghavi, et al.
Proceedings of the National Academy of Sciences of the United States of America|November 21, 2022
A blood-brain penetrant RNA-targeted small molecule triggers elimination of r(G<sub>4</sub>C<sub>2</sub>)<sup>exp</sup> in c9ALS/FTD via the nuclear RNA exosomeJessica A Bush, Samantha M Meyer, Rita Fuerst, et al.
Neurology and Therapy|October 17, 2023
Roadmap for C9ORF72 in Frontotemporal Dementia and Amyotrophic Lateral Sclerosis: Report on the C9ORF72 FTD/ALS SummitRita Sattler, Bryan J Traynor, Janice Robertson, et al.
Nature|May 24, 2023
Programming inactive RNA-binding small molecules into bioactive degradersYuquan Tong, Yeongju Lee, Xiaohui Liu, et al.
Cell Reports|May 7, 2020
Hexanucleotide Repeat Expansions in c9FTD/ALS and SCA36 Confer Selective Patterns of Neurodegeneration In VivoTiffany W Todd, Zachary T McEachin, Jeannie Chew, et al.
Science Translational Medicine|October 27, 2021
Ribonuclease recruitment using a small molecule reduced c9ALS/FTD r(G<sub>4</sub>C<sub>2</sub>) repeat expansion in vitro and in vivo ALS modelsJessica A Bush, Haruo Aikawa, Rita Fuerst, et al.
Neuron|August 19, 2014
Discovery of a biomarker and lead small molecules to target r(GGGGCC)-associated defects in c9FTD/ALSZhaoming Su, Yongjie Zhang, Tania F Gendron, et al.
Pageof 22

Showing results (201-210 of 213) with videos related to

Sort By:
Pageof 22
Molecular Neurodegeneration|February 16, 2019
Aberrant deposition of stress granule-resident proteins linked to C9orf72-associated TDP-43 proteinopathyJeannie Chew, Casey Cook, Tania F Gendron, et al.
Nature Communications|June 29, 2013
Induction and reversal of myotonic dystrophy type 1 pre-mRNA splicing defects by small moleculesJessica L Childs-Disney, Ewa Stepniak-Konieczna, Tuan Tran, et al.
Journal of the American Chemical Society|May 5, 2020
Design, Optimization, and Study of Small Molecules That Target Tau Pre-mRNA and Affect SplicingJonathan L Chen, Peiyuan Zhang, Masahito Abe, et al.
Journal of the American Chemical Society|October 6, 2025
Covalent Probes Reveal Small-Molecule Binding Pockets in Structured RNA and Enable Bioactive Compound DesignSandra Kovachka, Jielei Wang, Amirhossein Taghavi, et al.
Proceedings of the National Academy of Sciences of the United States of America|November 21, 2022
A blood-brain penetrant RNA-targeted small molecule triggers elimination of r(G<sub>4</sub>C<sub>2</sub>)<sup>exp</sup> in c9ALS/FTD via the nuclear RNA exosomeJessica A Bush, Samantha M Meyer, Rita Fuerst, et al.
Neurology and Therapy|October 17, 2023
Roadmap for C9ORF72 in Frontotemporal Dementia and Amyotrophic Lateral Sclerosis: Report on the C9ORF72 FTD/ALS SummitRita Sattler, Bryan J Traynor, Janice Robertson, et al.
Nature|May 24, 2023
Programming inactive RNA-binding small molecules into bioactive degradersYuquan Tong, Yeongju Lee, Xiaohui Liu, et al.
Cell Reports|May 7, 2020
Hexanucleotide Repeat Expansions in c9FTD/ALS and SCA36 Confer Selective Patterns of Neurodegeneration In VivoTiffany W Todd, Zachary T McEachin, Jeannie Chew, et al.
Science Translational Medicine|October 27, 2021
Ribonuclease recruitment using a small molecule reduced c9ALS/FTD r(G<sub>4</sub>C<sub>2</sub>) repeat expansion in vitro and in vivo ALS modelsJessica A Bush, Haruo Aikawa, Rita Fuerst, et al.
Neuron|August 19, 2014
Discovery of a biomarker and lead small molecules to target r(GGGGCC)-associated defects in c9FTD/ALSZhaoming Su, Yongjie Zhang, Tania F Gendron, et al.
Pageof 22