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Molecular & Cellular Proteomics : MCP
|
June 6, 2025
Soluble VCAM-1 May Serve as a Pharmacodynamic CSF Marker to Monitor BACE2 Activity in Non-Human Primates
Sarah K Tschirner, Y Joy Yu Zuchero, Jennifer A Getz, et al.
Scientific Reports
|
December 29, 2019
BACE1 partial deletion induces synaptic plasticity deficit in adult mice
Sylvia Lombardo, Martina Chiacchiaretta, Andrew Tarr, et al.
The Journal of Pharmacology and Experimental Therapeutics
|
January 31, 2016
Systems Pharmacology Analysis of the Amyloid Cascade after β-Secretase Inhibition Enables the Identification of an Aβ42 Oligomer Pool
Eline M T van Maanen, Tamara J van Steeg, Maria S Michener, et al.
The Journal of Pharmacology and Experimental Therapeutics
|
March 23, 2018
Extending a Systems Model of the APP Pathway: Separation of <i>β</i>- and <i>γ</i>-Secretase Sequential Cleavage Steps of APP
Eline M T van Maanen, Tamara J van Steeg, Maurice J Ahsman, et al.
Molecular Neurodegeneration
|
February 22, 2023
The Alzheimer's disease-linked protease BACE1 modulates neuronal IL-6 signaling through shedding of the receptor gp130
Stephan A Müller, Merav D Shmueli, Xiao Feng, et al.
Bioorganic & Medicinal Chemistry Letters
|
November 28, 2021
Design and discovery of C2-fluoroalkyl iminothiazine dioxides as BACE inhibitors
Brandon M Taoka, Wen-Lian Wu, Jinsong Hao, et al.
Brain : a Journal of Neurology
|
November 30, 2020
BACE inhibition causes rapid, regional, and non-progressive volume reduction in Alzheimer's disease brain
Cyrille Sur, James Kost, David Scott, et al.
NPJ Parkinson'S Disease
|
May 11, 2023
Glucocerebrosidase activity and lipid levels are related to protein pathologies in Parkinson's disease
Cheryl E G Leyns, Alice Prigent, Brenna Beezhold, et al.
The Journal of Pharmacology and Experimental Therapeutics
|
January 29, 2021
Characterization of the Onset, Progression, and Reversibility of Morphological Changes in Mouse Lung after Pharmacological Inhibition of Leucine-Rich Kinase 2 Kinase Activity
Dianne K Bryce, Chris M Ware, Janice D Woodhouse, et al.
Journal of Medicinal Chemistry
|
January 2, 2010
Application of fragment-based NMR screening, X-ray crystallography, structure-based design, and focused chemical library design to identify novel microM leads for the development of nM BACE-1 (beta-site APP cleaving enzyme 1) inhibitors
Yu-Sen Wang, Corey Strickland, Johannes H Voigt, et al.
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of 4
Search research articles
Search
Showing results (11-20 of 37) with videos related to
Sort By:
Page
of 4
Molecular & Cellular Proteomics : MCP
|
June 6, 2025
Soluble VCAM-1 May Serve as a Pharmacodynamic CSF Marker to Monitor BACE2 Activity in Non-Human Primates
Sarah K Tschirner, Y Joy Yu Zuchero, Jennifer A Getz, et al.
Scientific Reports
|
December 29, 2019
BACE1 partial deletion induces synaptic plasticity deficit in adult mice
Sylvia Lombardo, Martina Chiacchiaretta, Andrew Tarr, et al.
The Journal of Pharmacology and Experimental Therapeutics
|
January 31, 2016
Systems Pharmacology Analysis of the Amyloid Cascade after β-Secretase Inhibition Enables the Identification of an Aβ42 Oligomer Pool
Eline M T van Maanen, Tamara J van Steeg, Maria S Michener, et al.
The Journal of Pharmacology and Experimental Therapeutics
|
March 23, 2018
Extending a Systems Model of the APP Pathway: Separation of <i>β</i>- and <i>γ</i>-Secretase Sequential Cleavage Steps of APP
Eline M T van Maanen, Tamara J van Steeg, Maurice J Ahsman, et al.
Molecular Neurodegeneration
|
February 22, 2023
The Alzheimer's disease-linked protease BACE1 modulates neuronal IL-6 signaling through shedding of the receptor gp130
Stephan A Müller, Merav D Shmueli, Xiao Feng, et al.
Bioorganic & Medicinal Chemistry Letters
|
November 28, 2021
Design and discovery of C2-fluoroalkyl iminothiazine dioxides as BACE inhibitors
Brandon M Taoka, Wen-Lian Wu, Jinsong Hao, et al.
Brain : a Journal of Neurology
|
November 30, 2020
BACE inhibition causes rapid, regional, and non-progressive volume reduction in Alzheimer's disease brain
Cyrille Sur, James Kost, David Scott, et al.
NPJ Parkinson'S Disease
|
May 11, 2023
Glucocerebrosidase activity and lipid levels are related to protein pathologies in Parkinson's disease
Cheryl E G Leyns, Alice Prigent, Brenna Beezhold, et al.
The Journal of Pharmacology and Experimental Therapeutics
|
January 29, 2021
Characterization of the Onset, Progression, and Reversibility of Morphological Changes in Mouse Lung after Pharmacological Inhibition of Leucine-Rich Kinase 2 Kinase Activity
Dianne K Bryce, Chris M Ware, Janice D Woodhouse, et al.
Journal of Medicinal Chemistry
|
January 2, 2010
Application of fragment-based NMR screening, X-ray crystallography, structure-based design, and focused chemical library design to identify novel microM leads for the development of nM BACE-1 (beta-site APP cleaving enzyme 1) inhibitors
Yu-Sen Wang, Corey Strickland, Johannes H Voigt, et al.
Page
of 4